{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gurram V"],"funding":["NCRR NIH HHS","NIMHD NIH HHS"],"pagination":["451-462"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4340595"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["357(2-3)"],"pubmed_abstract":["Benzotriazoles are a highly important class of compounds with broad-ranging applications in such diverse areas as medicinal chemistry, as auxiliaries in organic synthesis, in metallurgical applications, in aircraft deicing and brake fluids, and as antifog agents in photography. Although there are numerous approaches to N-substituted benzotriazoles, the essentially one general method to N-unsubstituted benzotriazoles is via diazotization of <i>o</i>-phenylenediamines, which can be limited by the availability of suitable precursors. Other methods to N-unsubstitued benzotriazoles are quite specialized. Although reduction of 1-hydroxy-1<i>H</i>-benzotriazoles is known the reactions are not particularly convenient or broadly applicable. This presents a limitation for easy access to and availabi"],"journal":["Advanced synthesis & catalysis"],"pubmed_title":["Mild and General Access to Diverse 1<i>H</i>-Benzotriazoles via Diboron-Mediated N-OH Deoxygenation and Palladium-Catalyzed C-C and C-N Bond Formation."],"pmcid":["PMC4340595"],"funding_grant_id":["G12 RR003060","G12 MD007603"],"pubmed_authors":["Pottabathini N","Lakshman MK","Garlapati R","Gurram V","Akula HK"],"additional_accession":[]},"is_claimable":false,"name":"Mild and General Access to Diverse 1<i>H</i>-Benzotriazoles via Diboron-Mediated N-OH Deoxygenation and Palladium-Catalyzed C-C and C-N Bond Formation.","description":"Benzotriazoles are a highly important class of compounds with broad-ranging applications in such diverse areas as medicinal chemistry, as auxiliaries in organic synthesis, in metallurgical applications, in aircraft deicing and brake fluids, and as antifog agents in photography. Although there are numerous approaches to N-substituted benzotriazoles, the essentially one general method to N-unsubstituted benzotriazoles is via diazotization of <i>o</i>-phenylenediamines, which can be limited by the availability of suitable precursors. Other methods to N-unsubstitued benzotriazoles are quite specialized. Although reduction of 1-hydroxy-1<i>H</i>-benzotriazoles is known the reactions are not particularly convenient or broadly applicable. This presents a limitation for easy access to and availabi","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Feb","modification":"2025-04-27T15:36:11.538Z","creation":"2019-03-27T01:47:06Z"},"accession":"S-EPMC4340595","cross_references":{"pubmed":["25729343"],"doi":["10.1002/adsc.201400889"]}}