{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(2)"],"submitter":["Skora J"],"pubmed_abstract":["The aim of the study was to evaluate the ability of Alternaria isolates from workplaces to produce Alt a 1 allergenic protein, and to analyze whether technical materials (cellulose, compost, leather) present within the working environment stimulate or inhibit Alt a 1 production (ELISA test). Studies included identification of the isolated molds by nucleotide sequences analyzing of the ITS1/ITS2 regions, actin, calmodulin and Alt a 1 genes. It has been shown that Alternaria molds are significant part of microbiocenosis in the archive, museum, library, composting plant and tannery (14%-16% frequency in the air). The presence of the gene encoding the Alt a 1 protein has been detected for the strains: Alternaria alternata, A. lini, A. limoniasperae A. nobilis and A. tenuissima. Environmental s"],"journal":["International journal of environmental research and public health"],"pagination":["2164-83"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4344718"],"repository":["biostudies-literature"],"pubmed_title":["Production of the allergenic protein Alt a 1 by Alternaria isolates from working environments."],"pmcid":["PMC4344718"],"pubmed_authors":["Majak I","Stepien L","Otlewska A","Leszczynska J","Gutarowska B","Skora J"],"additional_accession":[]},"is_claimable":false,"name":"Production of the allergenic protein Alt a 1 by Alternaria isolates from working environments.","description":"The aim of the study was to evaluate the ability of Alternaria isolates from workplaces to produce Alt a 1 allergenic protein, and to analyze whether technical materials (cellulose, compost, leather) present within the working environment stimulate or inhibit Alt a 1 production (ELISA test). Studies included identification of the isolated molds by nucleotide sequences analyzing of the ITS1/ITS2 regions, actin, calmodulin and Alt a 1 genes. It has been shown that Alternaria molds are significant part of microbiocenosis in the archive, museum, library, composting plant and tannery (14%-16% frequency in the air). The presence of the gene encoding the Alt a 1 protein has been detected for the strains: Alternaria alternata, A. lini, A. limoniasperae A. nobilis and A. tenuissima. Environmental s","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Feb","modification":"2025-04-19T16:45:53.656Z","creation":"2020-11-19T13:25:07Z"},"accession":"S-EPMC4344718","cross_references":{"pubmed":["25689994"],"doi":["10.3390/ijerph120202164"]}}