biostudies-literatureUnknown16 Suppl 1INSIGHT Strategic Timing of AntiRetroviral Treatment (START) Study GroupNational Institute of Neurological Disorders and StrokeUK Medical Research Council and National Institute for Health ResearchFrench Agence Nationale de Recherches sur le SIDA et les Hépatites Virales (ANRS)NIAID NIH HHSNational Heart, Lung, and Blood InstituteGerman Ministry of Education and ResearchAustralian National Health and Medical Research CouncilEuropean AIDS Treatment Network (NEAT)Medical Research CouncilDepartment of Bioethics at the NIH Clinical CenterNational Cancer InstituteNational Institute of Allergy and Infectious Diseases of the National Institutes of HealthNational Institute of Arthritis and Musculoskeletal DisordersNational Institute of Mental HealthWellcome TrustHIV medicine1-9https://www.ebi.ac.uk/biostudies/studies/S-EPMC4347998biostudies-literatureWhy START? Reflections that led to the conduct of this large long-term strategic HIV trial.PMC4347998MC_UU_12023/23UM1 AI069423097410UM1 AI068641UM1 AI120197UM1 AI069415UM1-AI068641MC_U122886352UM1 AI069476Pillay DKoletar SKambili CMontes Ramirez MLCasseb JSequeira ABabiker AMenna MReiss PLalani TMcKernan SWorley Jde Burgh-Thomas AJohnson MABrekke KGoetz MMoussaoui TLa Rosa ALundgren JLevy YOrmaasen VRussell CChadwick DRTedaldi EPierone GEpperson KNovak RTouzeau VRClowes YSanz Sanz JLender HFisher MKegg SRattley MSanders AMisar KMeulbroek MCarr AWhite MChakvetadze CSantos RCheret ASchwarze Sde los Santo Gil IAnywaine ZEsser SRubio RFurrer HTurner DKityo CTurner MCrum-Cianflone NProschan MRoss JWhite DSouza TNYoshida CBGarofalo MMcKenna SThielman NSilvers Jdel Portal MMadero JSCuellar SCoburn PGordin FMCourtney-Rodgers DMacArthur RKatlama CBissio EHullsiek KHAldeguer JLHenry WPillay SJackson CMSeneviratne NReilly NMcGrath MJohansson LDaciuk LMuller NKagan JMRieger ASiddiqui SMuller VGompels 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SNVetter NAgan BKYogev RKiertiburanakul SNiewoehner DEGardner EDe Souza CLieunard CGanesan AJensen LPBowonwatanuwong CMendo FThiansanguankul WBagur JSLebas BSwanson NDavey RTLino SHudson FBica IYi APell CGoujard CBrown ALambert PArribas JRSalzberger BMorales DDavid DOFeind CJennings LKumar PFielder EHensley SDoroana MDebnam OCapitant CLecompte TParenti DKan VJilich DLibertone RStaub TFebo IDwyer DSarrach GVerdon RMcBurnett SDockrell DUbolyam SEid MLuz EWade BLundgren JDPacanowski JHiggs CGerstoft JLevitt JMarkowitz NMetallidis SSpector SRodriguez GGatell JMGordin FVandekerckhove LFrench MAzwa RILupo SBrew BSchultz TMitsuyasu RTHirschel BHarding JEmerson CKabeya KPopoola BCabot CCMakohon LMizuno GNetzer EBloch MPereira LCGeffen NYoule MLaplume HEKansau IHoy JAngus BGhosn JOtt ICampbell CSupparatpinyo KReuter TAvihingsanon AfalseWhy START? Reflections that led to the conduct of this large long-term strategic HIV trial.2015-01-01T00:00:00Z2015 Apr2025-04-19T04:14:43.466Z2025-04-19T04:14:43.466ZS-EPMC43479982571131710.1111/hiv.12227