{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["473(5)"],"submitter":["Wylie JD"],"pubmed_abstract":["<h4>Background</h4>Articular cartilage has minimal endogenous ability to undergo repair. Multiple chondral restoration strategies have been attempted with varied results.<h4>Questions/purposes</h4>The purpose of our review was to determine: (1) Does articular chondrocyte transplantation or matrix-assisted articular chondrocyte transplantation provide better patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue compared with microfracture in prospective comparative studies of articular cartilage repair; and (2) which available matrices for matrix-assisted articular chondrocyte transplantation show the best patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue?<h4>Methods</h4>We conducted a syst"],"journal":["Clinical orthopaedics and related research"],"pagination":["1673-82"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4385356"],"repository":["biostudies-literature"],"pubmed_title":["What is the effect of matrices on cartilage repair? A systematic review."],"pmcid":["PMC4385356"],"pubmed_authors":["Maak TG","Hartley MK","Kapron AL","Wylie JD","Aoki SK"],"additional_accession":[]},"is_claimable":false,"name":"What is the effect of matrices on cartilage repair? A systematic review.","description":"<h4>Background</h4>Articular cartilage has minimal endogenous ability to undergo repair. Multiple chondral restoration strategies have been attempted with varied results.<h4>Questions/purposes</h4>The purpose of our review was to determine: (1) Does articular chondrocyte transplantation or matrix-assisted articular chondrocyte transplantation provide better patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue compared with microfracture in prospective comparative studies of articular cartilage repair; and (2) which available matrices for matrix-assisted articular chondrocyte transplantation show the best patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue?<h4>Methods</h4>We conducted a syst","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 May","modification":"2026-05-07T17:43:19.205Z","creation":"2019-03-27T01:49:21Z"},"accession":"S-EPMC4385356","cross_references":{"pubmed":["25604876"],"doi":["10.1007/s11999-015-4141-0"]}}