biostudies-literatureUnknown473(5)Wylie JD<h4>Background</h4>Articular cartilage has minimal endogenous ability to undergo repair. Multiple chondral restoration strategies have been attempted with varied results.<h4>Questions/purposes</h4>The purpose of our review was to determine: (1) Does articular chondrocyte transplantation or matrix-assisted articular chondrocyte transplantation provide better patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue compared with microfracture in prospective comparative studies of articular cartilage repair; and (2) which available matrices for matrix-assisted articular chondrocyte transplantation show the best patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue?<h4>Methods</h4>We conducted a systClinical orthopaedics and related research1673-82https://www.ebi.ac.uk/biostudies/studies/S-EPMC4385356biostudies-literatureWhat is the effect of matrices on cartilage repair? A systematic review.PMC4385356Maak TGHartley MKKapron ALWylie JDAoki SKfalseWhat is the effect of matrices on cartilage repair? A systematic review.<h4>Background</h4>Articular cartilage has minimal endogenous ability to undergo repair. Multiple chondral restoration strategies have been attempted with varied results.<h4>Questions/purposes</h4>The purpose of our review was to determine: (1) Does articular chondrocyte transplantation or matrix-assisted articular chondrocyte transplantation provide better patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue compared with microfracture in prospective comparative studies of articular cartilage repair; and (2) which available matrices for matrix-assisted articular chondrocyte transplantation show the best patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue?<h4>Methods</h4>We conducted a syst2015-01-01T00:00:00Z2015 May2026-05-07T17:43:19.205Z2019-03-27T01:49:21ZS-EPMC43853562560487610.1007/s11999-015-4141-0