biostudies-literatureTangri NNCATS NIH HHSNIDDK NIH HHSPHS HHS667-75https://www.ebi.ac.uk/biostudies/studies/S-EPMC4402378biostudies-literatureUnknown30(4)<h4>Background</h4>Intravenous iron use in hemodialysis patients has greatly increased over the last decade, despite limited studies on the safety of iron.<h4>Methods</h4>We studied the association of receipt of intravenous iron with hospitalizations in an incident cohort of hemodialysis patients. We examined 9544 patients from Dialysis Clinic, Inc. (DCI). We ascertained intravenous iron use from DCI electronic medical record and USRDS data files, and hospitalizations through Medicare claims. We examined the association between iron exposure accumulated over 1-, 3- or 6-month time windows and incident hospitalizations in the follow-up period using marginal structural models accounting for time-dependent confounders. We performed sensitivity analyses including recurrent events models for muNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal AssociationEffect of intravenous iron use on hospitalizations in patients undergoing hemodialysis: a comparative effectiveness analysis from the DEcIDE-ESRD study.PMC4402378K23 DK095949K23DK083514K23 DK097184K23 DK083514UL1 TR001079K23DK095949UL1 TR001117HHSA290200500341ILiu JJaar BGNavaneethan SScheel PEbony Boulware LSchold JKim JMiskulin DCZager PEphraim PLiu XLiu YMichels WSt Peter WBandeen-Roche KHeubner BDEcIDE Network Patient Outcomes in End-Stage Renal Disease Study InvestigatorsGuo HCrews DCTangri NScialla JZhou JSozio SNally JMiskulin DJaar BKonig VArrigain SShafi TCrews DMeyer KSozio SMBoulware LEMichels WMScialla JJCook CEphraim PLCollins ACoresh JMcDermott ALuly JWu AFoley RJolly SHerzog CGilbertson DfalseEffect of intravenous iron use on hospitalizations in patients undergoing hemodialysis: a comparative effectiveness analysis from the DEcIDE-ESRD study.<h4>Background</h4>Intravenous iron use in hemodialysis patients has greatly increased over the last decade, despite limited studies on the safety of iron.<h4>Methods</h4>We studied the association of receipt of intravenous iron with hospitalizations in an incident cohort of hemodialysis patients. We examined 9544 patients from Dialysis Clinic, Inc. (DCI). We ascertained intravenous iron use from DCI electronic medical record and USRDS data files, and hospitalizations through Medicare claims. We examined the association between iron exposure accumulated over 1-, 3- or 6-month time windows and incident hospitalizations in the follow-up period using marginal structural models accounting for time-dependent confounders. We performed sensitivity analyses including recurrent events models for mu2015-01-01T00:00:00Z2015 Apr2025-04-19T00:48:05.812Z2019-03-27T01:50:07ZS-EPMC44023782536632810.1093/ndt/gfu349