{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(2)"],"submitter":["Xia T"],"pubmed_abstract":["<h4>Objective</h4>Several published literatures investigated the relation between a polymorphism (Leul25Val) in platelet endothelial cell adhesion molecule-1 (PECAM-1) gene and risk of coronary heart disease (CHD) and did not reach the same conclusion. To shed light on these inconclusive findings, we performed a meta-analysis of studies relating the PECAM-1 genetic polymorphism (Leul25Val) to the risk of CHD.<h4>Methods</h4>We identified literatures by searching PubMed, EMBASE, Chinese National Knowledge Infrastructure databases (CNKI) and Wanfang database in China. Data from eligible studies were extracted for meta-analysis. CHD risk associated with PECAM-1 genetic polymorphism (Leul25Val) was estimated by pooled odds ratios (ORs) and 95% confidence intervals (95% CIs). The software Revie"],"journal":["International journal of clinical and experimental medicine"],"pagination":["2219-25"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4402801"],"repository":["biostudies-literature"],"pubmed_title":["Association of Leu125Val polymorphisms in the PECAM-1 gene with the risk of coronary heartdisease: a meta-analysis."],"pmcid":["PMC4402801"],"pubmed_authors":["Liu X","Li G","Jin X","Du CJ","Kong XQ","Xia T"],"additional_accession":[]},"is_claimable":false,"name":"Association of Leu125Val polymorphisms in the PECAM-1 gene with the risk of coronary heartdisease: a meta-analysis.","description":"<h4>Objective</h4>Several published literatures investigated the relation between a polymorphism (Leul25Val) in platelet endothelial cell adhesion molecule-1 (PECAM-1) gene and risk of coronary heart disease (CHD) and did not reach the same conclusion. To shed light on these inconclusive findings, we performed a meta-analysis of studies relating the PECAM-1 genetic polymorphism (Leul25Val) to the risk of CHD.<h4>Methods</h4>We identified literatures by searching PubMed, EMBASE, Chinese National Knowledge Infrastructure databases (CNKI) and Wanfang database in China. Data from eligible studies were extracted for meta-analysis. CHD risk associated with PECAM-1 genetic polymorphism (Leul25Val) was estimated by pooled odds ratios (ORs) and 95% confidence intervals (95% CIs). The software Revie","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015","modification":"2025-04-20T01:14:33.276Z","creation":"2024-11-08T09:15:45.927Z"},"accession":"S-EPMC4402801","cross_references":{"pubmed":["25932154"]}}