{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19(5)"],"submitter":["Zhang X"],"pubmed_abstract":["Diabetes mellitus (DM) and breast cancer (BC) can simultaneously occur in the same patient populations, but the molecular relationship between them remains unknown. In this study, we constructed genetic networks and used modularized analysis approaches to investigate the multi-dimensional characteristics of two diseases and one disease subtype. A text search engine (Agilent Literature Search 2.71) and MCODE software were applied to validate potential subnetworks and to divide the modules, respectively. A total of 793 DM-related genes, 386 type 2 diabetes (T2DM) genes and 873 BC-related genes were identified from the Online Mendelian Inheritance in Man database. For DM and BC, a total of 99 overlapping genes, 9 modules, 29 biological processes and 7 pathways were identified. Meanwhile, for "],"journal":["Journal of cellular and molecular medicine"],"pagination":["1094-102"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4420611"],"repository":["biostudies-literature"],"pubmed_title":["Convergence and divergence of genetic and modular networks between diabetes and breast cancer."],"pmcid":["PMC4420611"],"pubmed_authors":["Li H","Liu J","Zhang Y","Zhang X","Wang J","Wang Z","Zhao Y","Yu Y","Yuan Y"],"additional_accession":[]},"is_claimable":false,"name":"Convergence and divergence of genetic and modular networks between diabetes and breast cancer.","description":"Diabetes mellitus (DM) and breast cancer (BC) can simultaneously occur in the same patient populations, but the molecular relationship between them remains unknown. In this study, we constructed genetic networks and used modularized analysis approaches to investigate the multi-dimensional characteristics of two diseases and one disease subtype. A text search engine (Agilent Literature Search 2.71) and MCODE software were applied to validate potential subnetworks and to divide the modules, respectively. A total of 793 DM-related genes, 386 type 2 diabetes (T2DM) genes and 873 BC-related genes were identified from the Online Mendelian Inheritance in Man database. For DM and BC, a total of 99 overlapping genes, 9 modules, 29 biological processes and 7 pathways were identified. Meanwhile, for ","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 May","modification":"2026-05-01T17:43:59.277Z","creation":"2026-04-07T17:10:00.127Z"},"accession":"S-EPMC4420611","cross_references":{"pubmed":["25752479"],"doi":["10.1111/jcmm.12504"]}}