{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Antwis RE"],"funding":["Natural Environment Research Council","Biotechnology and Biological Sciences Research Council"],"pagination":["3706-11"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4421062"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["81(11)"],"pubmed_abstract":["Microbiomes associated with multicellular organisms influence the disease susceptibility of hosts. The potential exists for such bacteria to protect wildlife from infectious diseases, particularly in the case of the globally distributed and highly virulent fungal pathogen Batrachochytrium dendrobatidis of the global panzootic lineage (B. dendrobatidis GPL), responsible for mass extinctions and population declines of amphibians. B. dendrobatidis GPL exhibits wide genotypic and virulence variation, and the ability of candidate probiotics to restrict growth across B. dendrobatidis isolates has not previously been considered. Here we show that only a small proportion of candidate probiotics exhibited broad-spectrum inhibition across B. dendrobatidis GPL isolates. Moreover, some bacterial gener"],"journal":["Applied and environmental microbiology"],"pubmed_title":["Amphibian Symbiotic Bacteria Do Not Show a Universal Ability To Inhibit Growth of the Global Panzootic Lineage of Batrachochytrium dendrobatidis."],"pmcid":["PMC4421062"],"funding_grant_id":["961801","NE/K012509/1"],"pubmed_authors":["Antwis RE","Harrison XA","Preziosi RF","Garner TW"],"additional_accession":[]},"is_claimable":false,"name":"Amphibian Symbiotic Bacteria Do Not Show a Universal Ability To Inhibit Growth of the Global Panzootic Lineage of Batrachochytrium dendrobatidis.","description":"Microbiomes associated with multicellular organisms influence the disease susceptibility of hosts. The potential exists for such bacteria to protect wildlife from infectious diseases, particularly in the case of the globally distributed and highly virulent fungal pathogen Batrachochytrium dendrobatidis of the global panzootic lineage (B. dendrobatidis GPL), responsible for mass extinctions and population declines of amphibians. B. dendrobatidis GPL exhibits wide genotypic and virulence variation, and the ability of candidate probiotics to restrict growth across B. dendrobatidis isolates has not previously been considered. Here we show that only a small proportion of candidate probiotics exhibited broad-spectrum inhibition across B. dendrobatidis GPL isolates. Moreover, some bacterial gener","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Jun","modification":"2026-05-02T01:38:56.932Z","creation":"2019-03-27T01:51:04Z"},"accession":"S-EPMC4421062","cross_references":{"pubmed":["25819964"],"doi":["10.1128/AEM.00010-15","10.1128/aem.00010-15"]}}