{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Takac T"],"funding":["European Social Fund","U.S. Department of Agriculture","Czech Science Foundation","Ministry of Education, Youth and Sports","NIGMS NIH HHS"],"pagination":["5347-61"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4423761"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(12)"],"pubmed_abstract":["Disentanglement of functional complexity associated with plant mitogen-activated protein kinase (MAPK) signaling has benefited from transcriptomic, proteomic, phosphoproteomic, and genetic studies. Published transcriptomic analysis of a double homozygous recessive anp2anp3 mutant of two MAPK kinase kinase (MAPKKK) genes called Arabidopsis thaliana Homologues of Nucleus- and Phragmoplast-localized Kinase 2 (ANP2) and 3 (ANP3) showed the upregulation of stress-related genes. In this study, a comparative proteomic analysis of anp2anp3 mutant against its respective Wassilevskaja ecotype (Ws) wild type background is provided. Such differential proteomic analysis revealed overabundance of core enzymes such as FeSOD1, MnSOD, DHAR1, and FeSOD1-associated regulatory protein CPN20, which are involve"],"journal":["Journal of proteome research"],"pubmed_title":["Proteomic and biochemical analyses show a functional network of proteins involved in antioxidant defense of the Arabidopsis anp2anp3 double mutant."],"pmcid":["PMC4423761"],"funding_grant_id":["CSREES 2009-34609-20222","CZ.1.07/2.3.00/20.0165","P501/11/1764","LO1204","P20 GM103476"],"pubmed_authors":["Pechan T","Vadovic P","Ovecka M","Komis G","Takac T","Kosutova P","Samaj J","Samajova O","Husickova A"],"additional_accession":[]},"is_claimable":false,"name":"Proteomic and biochemical analyses show a functional network of proteins involved in antioxidant defense of the Arabidopsis anp2anp3 double mutant.","description":"Disentanglement of functional complexity associated with plant mitogen-activated protein kinase (MAPK) signaling has benefited from transcriptomic, proteomic, phosphoproteomic, and genetic studies. Published transcriptomic analysis of a double homozygous recessive anp2anp3 mutant of two MAPK kinase kinase (MAPKKK) genes called Arabidopsis thaliana Homologues of Nucleus- and Phragmoplast-localized Kinase 2 (ANP2) and 3 (ANP3) showed the upregulation of stress-related genes. In this study, a comparative proteomic analysis of anp2anp3 mutant against its respective Wassilevskaja ecotype (Ws) wild type background is provided. Such differential proteomic analysis revealed overabundance of core enzymes such as FeSOD1, MnSOD, DHAR1, and FeSOD1-associated regulatory protein CPN20, which are involve","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Dec","modification":"2025-04-18T15:37:42.416Z","creation":"2019-03-27T01:51:12Z"},"accession":"S-EPMC4423761","cross_references":{"pubmed":["25325904"],"doi":["10.1021/pr500588c"]}}