{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Loux V"],"pubmed_abstract":["Background
Propionibacterium freudenreichii (PF) is an actinobacterium used in cheese technology and for its probiotic properties. PF is also extremely adaptable to several ecological niches and can grow on a variety of carbon and nitrogen sources. The aim of this work was to discover the genetic basis for strain-dependent traits related to its ability to use specific carbon sources. High-throughput sequencing technologies were ideal for this purpose as they have the potential to decipher genomic diversity at a moderate cost.Results
21 strains of PF were sequenced and the genomes were assembled de novo. Scaffolds were ordered by comparison with the complete reference genome CIRM-BIA1, obtained previously using traditional Sanger sequencing. Automatic functional annotation a"],"journal":["BMC genomics"],"pagination":["296"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4437456"],"repository":["biostudies-literature"],"pubmed_title":["Mutations and genomic islands can explain the strain dependency of sugar utilization in 21 strains of Propionibacterium freudenreichii."],"pmcid":["PMC4437456"],"pubmed_authors":["Almeida S","Parayre S","Le Loir Y","Chuat V","Buratti J","Peterlongo P","Azevedo V","Hammani A","Falentin H","Chiapello H","Madec MN","Gendrault A","Aury JM","Mariadassou M","Barbe V","Deutsch SM","Jan G","Loux V"],"additional_accession":[]},"is_claimable":false,"name":"Mutations and genomic islands can explain the strain dependency of sugar utilization in 21 strains of Propionibacterium freudenreichii.","description":"Background
Propionibacterium freudenreichii (PF) is an actinobacterium used in cheese technology and for its probiotic properties. PF is also extremely adaptable to several ecological niches and can grow on a variety of carbon and nitrogen sources. The aim of this work was to discover the genetic basis for strain-dependent traits related to its ability to use specific carbon sources. High-throughput sequencing technologies were ideal for this purpose as they have the potential to decipher genomic diversity at a moderate cost.Results
21 strains of PF were sequenced and the genomes were assembled de novo. Scaffolds were ordered by comparison with the complete reference genome CIRM-BIA1, obtained previously using traditional Sanger sequencing. Automatic functional annotation a","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Apr","modification":"2026-06-13T05:53:18.922Z","creation":"2019-03-27T01:51:52Z"},"accession":"S-EPMC4437456","cross_references":{"pubmed":["25886522"],"doi":["10.1186/s12864-015-1467-7"]}}