{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2015"],"submitter":["Castaldo G"],"funding":["A.O.R.N. "San Giuseppe Moscati""],"pubmed_abstract":["Background. Multiple weight loss failures among obese patients suggest the design of new therapeutic strategies. We investigated the role of 2-week course of enteral treatment with a very low-calorie protein-based formula in the management of severe obesity. Methods. We evaluated the feasibility, safety, and efficacy of 2-week continuous administration of a protein-based formula (1.2 g/kg of ideal body weight/day) by nasogastric tube in severely obese adults (body mass index (BMI) ≥ 40 kg/m(2)). Results. In total, 364 patients (59% women; BMI = 46.6 ± 7.2 kg/m(2)) were recruited. The intervention was discontinued within 48 hours in 26 patients, due to nasogastric tube intolerance. No serious adverse events occurred. During the first and the second week, 65% and 80% patients, respectively, "],"journal":["International journal of endocrinology"],"pagination":["723735"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4438151"],"repository":["biostudies-literature"],"pubmed_title":["A 2-Week Course of Enteral Treatment with a Very Low-Calorie Protein-Based Formula for the Management of Severe Obesity."],"pmcid":["PMC4438151"],"pubmed_authors":["Monaco L","Castaldo L","Sorrentino P","Castaldo G"],"additional_accession":[]},"is_claimable":false,"name":"A 2-Week Course of Enteral Treatment with a Very Low-Calorie Protein-Based Formula for the Management of Severe Obesity.","description":"Background. Multiple weight loss failures among obese patients suggest the design of new therapeutic strategies. We investigated the role of 2-week course of enteral treatment with a very low-calorie protein-based formula in the management of severe obesity. Methods. We evaluated the feasibility, safety, and efficacy of 2-week continuous administration of a protein-based formula (1.2 g/kg of ideal body weight/day) by nasogastric tube in severely obese adults (body mass index (BMI) ≥ 40 kg/m(2)). Results. In total, 364 patients (59% women; BMI = 46.6 ± 7.2 kg/m(2)) were recruited. The intervention was discontinued within 48 hours in 26 patients, due to nasogastric tube intolerance. No serious adverse events occurred. During the first and the second week, 65% and 80% patients, respectively, ","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015","modification":"2026-05-02T05:09:22.506Z","creation":"2019-03-27T01:51:54Z"},"accession":"S-EPMC4438151","cross_references":{"pubmed":["26064113"],"doi":["10.1155/2015/723735"]}}