biostudies-literatureUnknown15Jurickova I<h4>Background</h4>Heliox is a mixture of oxygen and helium which reduces airway resistance in patients with airway obstruction. In clinical practice, patients breathing spontaneously receive heliox via an open circuit. Recently, a semi-closed circuit for heliox administration has been proposed which minimizes consumption of heliox and therefore cost of the heliox therapy; although, the semi-closed circuit is associated with additional costs. The aim of the study is to conduct an economical analysis comparing total cost of heliox therapy using an open versus a semi-closed circuit in spontaneously breathing patients with airway obstruction.<h4>Methods</h4>Four different systems for heliox administration were analyzed: an open circuit and three alternatives of a semi-closed circuit involvingBMC pulmonary medicine65https://www.ebi.ac.uk/biostudies/studies/S-EPMC4460863biostudies-literatureDelivery of heliox with a semi-closed circuit during spontaneous breathing: a comparative economic theoretical study.PMC4460863Muller MRoubik KJurickova IfalseDelivery of heliox with a semi-closed circuit during spontaneous breathing: a comparative economic theoretical study.<h4>Background</h4>Heliox is a mixture of oxygen and helium which reduces airway resistance in patients with airway obstruction. In clinical practice, patients breathing spontaneously receive heliox via an open circuit. Recently, a semi-closed circuit for heliox administration has been proposed which minimizes consumption of heliox and therefore cost of the heliox therapy; although, the semi-closed circuit is associated with additional costs. The aim of the study is to conduct an economical analysis comparing total cost of heliox therapy using an open versus a semi-closed circuit in spontaneously breathing patients with airway obstruction.<h4>Methods</h4>Four different systems for heliox administration were analyzed: an open circuit and three alternatives of a semi-closed circuit involving2015-01-01T00:00:00Z2015 Jun2025-04-22T01:14:39.451Z2019-03-27T01:53:08ZS-EPMC44608632605911110.1186/s12890-015-0060-9