{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fairburn CG"],"funding":["Wellcome Trust"],"pagination":["64-71"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4461007"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["70"],"pubmed_abstract":["Eating disorders may be viewed from a transdiagnostic perspective and there is evidence supporting a transdiagnostic form of cognitive behaviour therapy (CBT-E). The aim of the present study was to compare CBT-E with interpersonal psychotherapy (IPT), a leading alternative treatment for adults with an eating disorder. One hundred and thirty patients with any form of eating disorder (body mass index >17.5 to <40.0) were randomized to either CBT-E or IPT. Both treatments involved 20 sessions over 20 weeks followed by a 60-week closed follow-up period. Outcome was measured by independent blinded assessors. Twenty-nine participants (22.3%) did not complete treatment or were withdrawn. At post-treatment 65.5% of the CBT-E participants met criteria for remission compared with 33.3% of the IPT participants (p < 0.001). Over follow-up the proportion of participants meeting criteria for remission increased, particularly in the IPT condition, but the CBT-E remission rate remained higher (CBT-E 69.4%, IPT 49.0%; p = 0.028). The response to CBT-E was very similar to that observed in an earlier study. The findings indicate that CBT-E is potent treatment for the majority of outpatients with an eating disorder. IPT remains an alternative to CBT-E, but the response is less pronounced and slower to be expressed.<h4>Current controlled trials</h4>ISRCTN 15562271."],"journal":["Behaviour research and therapy"],"pubmed_title":["A transdiagnostic comparison of enhanced cognitive behaviour therapy (CBT-E) and interpersonal psychotherapy in the treatment of eating disorders."],"pmcid":["PMC4461007"],"funding_grant_id":["046386","094585","079113/Z/06/Z","079113"],"pubmed_authors":["O'Connor ME","Cooper Z","Basden S","Fairburn CG","Bailey-Straebler S","Doll HA","Jones R","Murphy R"],"additional_accession":[]},"is_claimable":false,"name":"A transdiagnostic comparison of enhanced cognitive behaviour therapy (CBT-E) and interpersonal psychotherapy in the treatment of eating disorders.","description":"Eating disorders may be viewed from a transdiagnostic perspective and there is evidence supporting a transdiagnostic form of cognitive behaviour therapy (CBT-E). The aim of the present study was to compare CBT-E with interpersonal psychotherapy (IPT), a leading alternative treatment for adults with an eating disorder. One hundred and thirty patients with any form of eating disorder (body mass index >17.5 to <40.0) were randomized to either CBT-E or IPT. Both treatments involved 20 sessions over 20 weeks followed by a 60-week closed follow-up period. Outcome was measured by independent blinded assessors. Twenty-nine participants (22.3%) did not complete treatment or were withdrawn. At post-treatment 65.5% of the CBT-E participants met criteria for remission compared with 33.3% of the IPT participants (p < 0.001). Over follow-up the proportion of participants meeting criteria for remission increased, particularly in the IPT condition, but the CBT-E remission rate remained higher (CBT-E 69.4%, IPT 49.0%; p = 0.028). The response to CBT-E was very similar to that observed in an earlier study. The findings indicate that CBT-E is potent treatment for the majority of outpatients with an eating disorder. IPT remains an alternative to CBT-E, but the response is less pronounced and slower to be expressed.<h4>Current controlled trials</h4>ISRCTN 15562271.","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Jul","modification":"2025-04-04T07:30:01.501Z","creation":"2019-03-27T01:53:09Z"},"accession":"S-EPMC4461007","cross_references":{"pubmed":["26000757"],"doi":["10.1016/j.brat.2015.04.010"]}}