biostudies-literatureMagalhaes da Silva TNIAID NIH HHS984-9https://www.ebi.ac.uk/biostudies/studies/S-EPMC4463503biostudies-literatureUnknown23(7)The degree of admixture in Brazil between historically isolated populations is complex and geographically variable. Studies differ as to what the genetic and phenotypic consequences of this mixing have been. In Northeastern Brazil, we enrolled 522 residents of Salvador and 620 of Fortaleza whose distributions of self-declared color were comparable to those in the national census. Using the program Structure and principal components analysis there was a clear correlation between biogeographic ancestry and categories of skin color. This correlation with African ancestry was stronger in Salvador (r=0.585; P<0.001) than in Fortaleza (r=0.236; P<0.001). In Fortaleza, although self-declared blacks had a greater proportion of European ancestry, they had more African ancestry than the other categoEuropean journal of human genetics : EJHGThe correlation between ancestry and color in two cities of Northeast Brazil with contrasting ethnic compositions.PMC4463503(R21 AI056263R21 AI056263Nascimento JFSandhya Rani MRFigueiredo MAde Oliveira Costa GNMelo PSBarreto MLMagalhaes da Silva TMolyneaux NDReis MGBlanton RETeixeira MGfalseThe correlation between ancestry and color in two cities of Northeast Brazil with contrasting ethnic compositions.The degree of admixture in Brazil between historically isolated populations is complex and geographically variable. Studies differ as to what the genetic and phenotypic consequences of this mixing have been. In Northeastern Brazil, we enrolled 522 residents of Salvador and 620 of Fortaleza whose distributions of self-declared color were comparable to those in the national census. Using the program Structure and principal components analysis there was a clear correlation between biogeographic ancestry and categories of skin color. This correlation with African ancestry was stronger in Salvador (r=0.585; P<0.001) than in Fortaleza (r=0.236; P<0.001). In Fortaleza, although self-declared blacks had a greater proportion of European ancestry, they had more African ancestry than the other catego2015-01-01T00:00:00Z2015 Jul2026-05-04T04:44:38.918Z2019-03-27T01:53:16ZS-EPMC44635032529371810.1038/ejhg.2014.215