biostudies-literaturePrimer DNPfizerNational Institutes of HealthNIGMS NIH HHSTubitak2195-8https://www.ebi.ac.uk/biostudies/studies/S-EPMC4466116biostudies-literatureUnknown137(6)Single-electron-mediated alkyl transfer affords a novel mechanism for transmetalation, enabling cross-coupling under mild conditions. Here, general conditions are reported for cross-coupling of secondary alkyltrifluoroborates with an array of aryl bromides mediated by an Ir photoredox catalyst and a Ni cross-coupling catalyst.Journal of the American Chemical SocietySingle-electron transmetalation: an enabling technology for secondary alkylboron cross-coupling.PMC4466116R01 GM081376NIGMS R01 GM081376Karakaya IMolander GAPrimer DNTellis JCfalseSingle-electron transmetalation: an enabling technology for secondary alkylboron cross-coupling.Single-electron-mediated alkyl transfer affords a novel mechanism for transmetalation, enabling cross-coupling under mild conditions. Here, general conditions are reported for cross-coupling of secondary alkyltrifluoroborates with an array of aryl bromides mediated by an Ir photoredox catalyst and a Ni cross-coupling catalyst.2015-01-01T00:00:00Z2015 Feb2026-05-01T14:48:41.909Z2026-04-07T17:03:21.01ZS-EPMC44661162565089210.1021/ja512946e