{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(6)"],"submitter":["Dhondt A"],"pubmed_abstract":["<h4>Background and objective</h4>Low molecular weight heparins (LMWHs) are small enough to pass large pore dialysis membranes. Removal of LMWH if injected before the start of the session is possible during high-flux dialysis and hemodiafiltration. The aim of this study was to determine the optimal mode (place and time) of tinzaparin administration during postdilution hemodiafiltration.<h4>Study design, setting, patients</h4>In 13 chronic hemodiafiltration patients, 3 approaches of injection were compared in a randomised cross over trial: i) before the start of the session at the inlet blood line filled with rinsing solution (IN0), ii) 5 min after the start at the inlet line filled with blood (IN5) and iii) before the start of the session at the outlet blood line (OUT0). Anti-Xa activity, t"],"journal":["PloS one"],"pagination":["e0128634"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4468116"],"repository":["biostudies-literature"],"pubmed_title":["Where and When To Inject Low Molecular Weight Heparin in Hemodiafiltration? A Cross Over Randomised Trial."],"pmcid":["PMC4468116"],"pubmed_authors":["Glorieux G","Vanholder R","Eloot S","Dhondt A","Pauwels R","Devreese K"],"additional_accession":[]},"is_claimable":false,"name":"Where and When To Inject Low Molecular Weight Heparin in Hemodiafiltration? A Cross Over Randomised Trial.","description":"<h4>Background and objective</h4>Low molecular weight heparins (LMWHs) are small enough to pass large pore dialysis membranes. Removal of LMWH if injected before the start of the session is possible during high-flux dialysis and hemodiafiltration. The aim of this study was to determine the optimal mode (place and time) of tinzaparin administration during postdilution hemodiafiltration.<h4>Study design, setting, patients</h4>In 13 chronic hemodiafiltration patients, 3 approaches of injection were compared in a randomised cross over trial: i) before the start of the session at the inlet blood line filled with rinsing solution (IN0), ii) 5 min after the start at the inlet line filled with blood (IN5) and iii) before the start of the session at the outlet blood line (OUT0). Anti-Xa activity, t","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015","modification":"2026-05-30T08:37:08.264Z","creation":"2019-03-26T23:33:17Z"},"accession":"S-EPMC4468116","cross_references":{"pubmed":["26076014"],"doi":["10.1371/journal.pone.0128634"]}}