{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wolters AM"],"funding":["Netherlands Top Consortium for Knowledge and Innovation","The Major Project of Chinese National Programs for Fundamental Research and Development","National Natural Science Foundation of China"],"pagination":["1987-97"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4572051"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["128(10)"],"pubmed_abstract":["<h4>Key message</h4>A chromosomal inversion associated with the tomato Ty - 2 gene for TYLCV resistance is the cause of severe suppression of recombination in a tomato Ty - 2 introgression line. Among tomato and its wild relatives inversions are often observed, which result in suppression of recombination. Such inversions hamper the transfer of important traits from a related species to the crop by introgression breeding. Suppression of recombination was reported for the TYLCV resistance gene, Ty-2, which has been introgressed in cultivated tomato (Solanum lycopersicum) from the wild relative S. habrochaites accession B6013. Ty-2 was mapped to a 300-kb region on the long arm of chromosome 11. The suppression of recombination in the Ty-2 region could be caused by chromosomal rearrangements "],"journal":["TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik"],"pubmed_title":["Detection of an inversion in the Ty-2 region between S. lycopersicum and S. habrochaites by a combination of de novo genome assembly and BAC cloning."],"pmcid":["PMC4572051"],"funding_grant_id":["TU-370","31372070","2011CB100600"],"pubmed_authors":["Finkers R","Visser RG","Caro M","Gao J","Du Y","Wang X","Bai Y","Wolters AM","Dong S"],"additional_accession":[]},"is_claimable":false,"name":"Detection of an inversion in the Ty-2 region between S. lycopersicum and S. habrochaites by a combination of de novo genome assembly and BAC cloning.","description":"<h4>Key message</h4>A chromosomal inversion associated with the tomato Ty - 2 gene for TYLCV resistance is the cause of severe suppression of recombination in a tomato Ty - 2 introgression line. Among tomato and its wild relatives inversions are often observed, which result in suppression of recombination. Such inversions hamper the transfer of important traits from a related species to the crop by introgression breeding. Suppression of recombination was reported for the TYLCV resistance gene, Ty-2, which has been introgressed in cultivated tomato (Solanum lycopersicum) from the wild relative S. habrochaites accession B6013. Ty-2 was mapped to a 300-kb region on the long arm of chromosome 11. The suppression of recombination in the Ty-2 region could be caused by chromosomal rearrangements ","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Oct","modification":"2026-05-03T01:21:16.996Z","creation":"2019-03-27T01:58:29Z"},"accession":"S-EPMC4572051","cross_references":{"pubmed":["26152571"],"doi":["10.1007/s00122-015-2561-6"]}}