biostudies-literatureWolters AMNetherlands Top Consortium for Knowledge and InnovationThe Major Project of Chinese National Programs for Fundamental Research and DevelopmentNational Natural Science Foundation of China1987-97https://www.ebi.ac.uk/biostudies/studies/S-EPMC4572051biostudies-literatureUnknown128(10)<h4>Key message</h4>A chromosomal inversion associated with the tomato Ty - 2 gene for TYLCV resistance is the cause of severe suppression of recombination in a tomato Ty - 2 introgression line. Among tomato and its wild relatives inversions are often observed, which result in suppression of recombination. Such inversions hamper the transfer of important traits from a related species to the crop by introgression breeding. Suppression of recombination was reported for the TYLCV resistance gene, Ty-2, which has been introgressed in cultivated tomato (Solanum lycopersicum) from the wild relative S. habrochaites accession B6013. Ty-2 was mapped to a 300-kb region on the long arm of chromosome 11. The suppression of recombination in the Ty-2 region could be caused by chromosomal rearrangements TAG. Theoretical and applied genetics. Theoretische und angewandte GenetikDetection of an inversion in the Ty-2 region between S. lycopersicum and S. habrochaites by a combination of de novo genome assembly and BAC cloning.PMC4572051TU-370313720702011CB100600Finkers RVisser RGCaro MGao JDu YWang XBai YWolters AMDong SfalseDetection of an inversion in the Ty-2 region between S. lycopersicum and S. habrochaites by a combination of de novo genome assembly and BAC cloning.<h4>Key message</h4>A chromosomal inversion associated with the tomato Ty - 2 gene for TYLCV resistance is the cause of severe suppression of recombination in a tomato Ty - 2 introgression line. Among tomato and its wild relatives inversions are often observed, which result in suppression of recombination. Such inversions hamper the transfer of important traits from a related species to the crop by introgression breeding. Suppression of recombination was reported for the TYLCV resistance gene, Ty-2, which has been introgressed in cultivated tomato (Solanum lycopersicum) from the wild relative S. habrochaites accession B6013. Ty-2 was mapped to a 300-kb region on the long arm of chromosome 11. The suppression of recombination in the Ty-2 region could be caused by chromosomal rearrangements 2015-01-01T00:00:00Z2015 Oct2026-05-03T01:21:16.996Z2019-03-27T01:58:29ZS-EPMC45720512615257110.1007/s00122-015-2561-6