{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Minissian M"],"funding":["NCATS NIH HHS","NCRR NIH HHS","NIA NIH HHS","NHLBI NIH HHS","PHS HHS"],"pagination":["449"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4574117"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8"],"pubmed_abstract":["<h4>Background</h4>Statin intolerance is often due to myalgias. Severe vitamin D deficiency is characterized by musculoskeletal pain. We hypothesized that statin-intolerance is associated with vitamin D deficiency.<h4>Objectives</h4>To determine whether there is an association between statin-intolerance and vitamin D deficiency in a retrospective observational analysis.<h4>Methods</h4>We evaluated 20 female patients with prior myalgia-related daily dose statin intolerance on an alternative day statin dosing protocol of twice weekly for 4 weeks followed by advancement to daily dosing, as tolerated. Fasting baseline and follow-up lipid and 25-hydroxy-vitamin D (25-OHD) levels were obtained by chart review.<h4>Results</h4>The group median age was 61 ± 13 years old and BMI was 27 ± 7 kg/m(2). "],"journal":["BMC research notes"],"pubmed_title":["Do women with statin-related myalgias have low vitamin D levels?"],"pmcid":["PMC4574117"],"funding_grant_id":["UL1 TR000064","UL1TR000124","T32HL69751","U01 HL649141","UL1 TR000124","U01 HL649241","N01-HV-68163","N01-HV-68162","N01HV68163","N01HV68162","UL1TR000064","UL1 TR001427","R01 HL090957","1R03AG032631","K23HL105787","K23 HL105787","M01 RR000425","U0164829","N01 HV068164","T32 HL069751","R03 AG032631","M01-RR00425","N01 HV068161"],"pubmed_authors":["Agarwal M","Lentz G","Noel Bairey Merz C","Minissian M","Cook-Wiens G","Shufelt C","Mehta PK","Eastwood JA","Waldman T"],"additional_accession":[]},"is_claimable":false,"name":"Do women with statin-related myalgias have low vitamin D levels?","description":"<h4>Background</h4>Statin intolerance is often due to myalgias. Severe vitamin D deficiency is characterized by musculoskeletal pain. We hypothesized that statin-intolerance is associated with vitamin D deficiency.<h4>Objectives</h4>To determine whether there is an association between statin-intolerance and vitamin D deficiency in a retrospective observational analysis.<h4>Methods</h4>We evaluated 20 female patients with prior myalgia-related daily dose statin intolerance on an alternative day statin dosing protocol of twice weekly for 4 weeks followed by advancement to daily dosing, as tolerated. Fasting baseline and follow-up lipid and 25-hydroxy-vitamin D (25-OHD) levels were obtained by chart review.<h4>Results</h4>The group median age was 61 ± 13 years old and BMI was 27 ± 7 kg/m(2). ","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Sep","modification":"2025-04-26T21:51:28.343Z","creation":"2019-03-27T01:58:36Z"},"accession":"S-EPMC4574117","cross_references":{"pubmed":["26382747"],"doi":["10.1186/s13104-015-1356-9"]}}