biostudies-literatureMinissian MNCATS NIH HHSNCRR NIH HHSNIA NIH HHSNHLBI NIH HHSPHS HHS449https://www.ebi.ac.uk/biostudies/studies/S-EPMC4574117biostudies-literatureUnknown8<h4>Background</h4>Statin intolerance is often due to myalgias. Severe vitamin D deficiency is characterized by musculoskeletal pain. We hypothesized that statin-intolerance is associated with vitamin D deficiency.<h4>Objectives</h4>To determine whether there is an association between statin-intolerance and vitamin D deficiency in a retrospective observational analysis.<h4>Methods</h4>We evaluated 20 female patients with prior myalgia-related daily dose statin intolerance on an alternative day statin dosing protocol of twice weekly for 4 weeks followed by advancement to daily dosing, as tolerated. Fasting baseline and follow-up lipid and 25-hydroxy-vitamin D (25-OHD) levels were obtained by chart review.<h4>Results</h4>The group median age was 61 ± 13 years old and BMI was 27 ± 7 kg/m(2). BMC research notesDo women with statin-related myalgias have low vitamin D levels?PMC4574117UL1 TR000064UL1TR000124T32HL69751U01 HL649141UL1 TR000124U01 HL649241N01-HV-68163N01-HV-68162N01HV68163N01HV68162UL1TR000064UL1 TR001427R01 HL0909571R03AG032631K23HL105787K23 HL105787M01 RR000425U0164829N01 HV068164T32 HL069751R03 AG032631M01-RR00425N01 HV068161Agarwal MLentz GNoel Bairey Merz CMinissian MCook-Wiens GShufelt CMehta PKEastwood JAWaldman TfalseDo women with statin-related myalgias have low vitamin D levels?<h4>Background</h4>Statin intolerance is often due to myalgias. Severe vitamin D deficiency is characterized by musculoskeletal pain. We hypothesized that statin-intolerance is associated with vitamin D deficiency.<h4>Objectives</h4>To determine whether there is an association between statin-intolerance and vitamin D deficiency in a retrospective observational analysis.<h4>Methods</h4>We evaluated 20 female patients with prior myalgia-related daily dose statin intolerance on an alternative day statin dosing protocol of twice weekly for 4 weeks followed by advancement to daily dosing, as tolerated. Fasting baseline and follow-up lipid and 25-hydroxy-vitamin D (25-OHD) levels were obtained by chart review.<h4>Results</h4>The group median age was 61 ± 13 years old and BMI was 27 ± 7 kg/m(2). 2015-01-01T00:00:00Z2015 Sep2025-04-26T21:51:28.343Z2019-03-27T01:58:36ZS-EPMC45741172638274710.1186/s13104-015-1356-9