{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Reynders A"],"funding":["European Research Council"],"pagination":["132-5"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4583636"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5"],"pubmed_abstract":["The skin is the largest sensory organ that is densely innervated by highly specialized sensory neurons allowing the detection of a wide range of stimulations including light touch, temperature, itch and pain. Our knowledge of the sets of genes instructing the functional specialization of sensory neurons is just emerging. In a previous study, we have identified a new Gαi inhibitory interacting protein (GINIP) that marks two distinct subsets of skin-innervating sensory neurons conveying noxious and pleasant touch: the MRGPRD-expressing C-fibers specialized in noxious touch and the TH(+)/TAFA4(+)/V-GLUT3(+) C-Low Threshold MechanoReceptors (C-LTMRs), part of neurons processing pleasant touch. In the recent study published by Reynders et al. (2015), we took advantage of GINIP(mCherry) mouse mo"],"journal":["Genomics data"],"pubmed_title":["Analysis of cutaneous MRGPRD free nerve endings and C-LTMRs transcriptomes by RNA-sequencing."],"pmcid":["PMC4583636"],"funding_grant_id":["260435"],"pubmed_authors":["Reynders A","Moqrich A"],"additional_accession":[]},"is_claimable":false,"name":"Analysis of cutaneous MRGPRD free nerve endings and C-LTMRs transcriptomes by RNA-sequencing.","description":"The skin is the largest sensory organ that is densely innervated by highly specialized sensory neurons allowing the detection of a wide range of stimulations including light touch, temperature, itch and pain. Our knowledge of the sets of genes instructing the functional specialization of sensory neurons is just emerging. In a previous study, we have identified a new Gαi inhibitory interacting protein (GINIP) that marks two distinct subsets of skin-innervating sensory neurons conveying noxious and pleasant touch: the MRGPRD-expressing C-fibers specialized in noxious touch and the TH(+)/TAFA4(+)/V-GLUT3(+) C-Low Threshold MechanoReceptors (C-LTMRs), part of neurons processing pleasant touch. In the recent study published by Reynders et al. (2015), we took advantage of GINIP(mCherry) mouse mo","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Sep","modification":"2025-04-22T14:17:18.964Z","creation":"2019-06-06T14:54:41Z"},"accession":"S-EPMC4583636","cross_references":{"pubmed":["26484241"],"doi":["10.1016/j.gdata.2015.05.022"]}}