biostudies-literatureUnknown5Chung YHWe demonstrate an analog type logical device that combines metalloprotein and organic/inorganic materials and can make an interactive analog decision. Myoglobin is used as a functional biomolecule to generate electrochemical signals, and its original redox signal is controlled with various mercapto-acids by the distance effect between myoglobin and a metal surface in the process of electron transfer. Controlled signals are modulated with the introduction of inorganic materials including nanoparticles and metal ions. By forming a hybrid structure with various constituents of organic/inorganic materials, several functions for signal manipulation were achieved, including enhancement, suppression, and shift. Based on the manipulated signals of biomolecules, a novel logical system for interactiScientific reports14501https://www.ebi.ac.uk/biostudies/studies/S-EPMC4585857biostudies-literatureElectrochemical Bioelectronic Device Consisting of Metalloprotein for Analog Decision Making.PMC4585857Min JYoo SYChoi JWChung YHLee TfalseElectrochemical Bioelectronic Device Consisting of Metalloprotein for Analog Decision Making.We demonstrate an analog type logical device that combines metalloprotein and organic/inorganic materials and can make an interactive analog decision. Myoglobin is used as a functional biomolecule to generate electrochemical signals, and its original redox signal is controlled with various mercapto-acids by the distance effect between myoglobin and a metal surface in the process of electron transfer. Controlled signals are modulated with the introduction of inorganic materials including nanoparticles and metal ions. By forming a hybrid structure with various constituents of organic/inorganic materials, several functions for signal manipulation were achieved, including enhancement, suppression, and shift. Based on the manipulated signals of biomolecules, a novel logical system for interacti2015-01-01T00:00:00Z2015 Sep2025-04-21T20:22:56.451Z2019-03-27T01:59:07ZS-EPMC45858572640001810.1038/srep14501