{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tong H"],"funding":["NCRR NIH HHS"],"pagination":["1173-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4629741"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["123(11)"],"pubmed_abstract":["<h4>Background</h4>Exposure to ambient particulate matter (PM) induces endothelial dysfunction, a risk factor for cardiovascular disease. Olive oil (OO) and fish oil (FO) supplements have beneficial effects on endothelial function.<h4>Objective</h4>In this study we evaluated the potential efficacy of OO and FO in mitigating endothelial dysfunction and disruption of hemostasis caused by exposure to particulate matter (PM).<h4>Methods and results</h4>Forty-two participants (58 ± 1 years of age) received either 3 g/day of OO or FO, or no supplements (naive) for 4 weeks prior to undergoing 2-hr exposures to filtered air and concentrated ambient particulate matter (CAP; mean, 253 ± 16 μg/m3). Endothelial function was assessed by flow-mediated dilation (FMD) of the brachial artery preexposure, i"],"journal":["Environmental health perspectives"],"pubmed_title":["Dietary Supplementation with Olive Oil or Fish Oil and Vascular Effects of Concentrated Ambient Particulate Matter Exposure in Human Volunteers."],"pmcid":["PMC4629741"],"funding_grant_id":["RR00046","M01 RR000046"],"pubmed_authors":["Bromberg PA","Cascio WE","Berntsen J","Diaz-Sanchez D","Case MW","Hinderliter AL","Rappold AG","Bassett M","Samet JM","Caughey M","Tong H","Montilla T","Devlin RB"],"additional_accession":[]},"is_claimable":false,"name":"Dietary Supplementation with Olive Oil or Fish Oil and Vascular Effects of Concentrated Ambient Particulate Matter Exposure in Human Volunteers.","description":"<h4>Background</h4>Exposure to ambient particulate matter (PM) induces endothelial dysfunction, a risk factor for cardiovascular disease. Olive oil (OO) and fish oil (FO) supplements have beneficial effects on endothelial function.<h4>Objective</h4>In this study we evaluated the potential efficacy of OO and FO in mitigating endothelial dysfunction and disruption of hemostasis caused by exposure to particulate matter (PM).<h4>Methods and results</h4>Forty-two participants (58 ± 1 years of age) received either 3 g/day of OO or FO, or no supplements (naive) for 4 weeks prior to undergoing 2-hr exposures to filtered air and concentrated ambient particulate matter (CAP; mean, 253 ± 16 μg/m3). Endothelial function was assessed by flow-mediated dilation (FMD) of the brachial artery preexposure, i","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Nov","modification":"2025-04-05T14:29:46.8Z","creation":"2019-03-27T02:01:10Z"},"accession":"S-EPMC4629741","cross_references":{"pubmed":["25933197"],"doi":["10.1289/ehp.1408988"]}}