{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["80(5)"],"submitter":["Lai CL"],"pubmed_abstract":["<h4>Aims</h4>This study aimed to evaluate the risk of hip/femur fractures during the initiation period of α-adrenoceptor blocker therapy using the National Health Insurance claims database, Taiwan, with a self-controlled case series design.<h4>Methods</h4>All male beneficiaries aged over 50 years as of 2007, who were incident users of α-adrenoceptor blockers and also had a diagnosis of hip/femur fracture within the 2007-2009 study period were identified. The first day when the α-adrenoceptor blocker was prescribed was set as the index date. We partitioned the initial 21 day period following the index date as the post-exposure risk period 1, days 22-60 after the index date as the post-exposure risk period 2, the 21 day period prior to the index date as the pre-exposure risk period 1 and day"],"journal":["British journal of clinical pharmacology"],"pagination":["1208-18"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4631193"],"repository":["biostudies-literature"],"pubmed_title":["Risk of hip/femur fractures during the initiation period of α-adrenoceptor blocker therapy among elderly males: a self-controlled case series study."],"pmcid":["PMC4631193"],"pubmed_authors":["Chen MF","Lai CL","Lai MS","Chan KA","Kuo RN","Chen HM"],"additional_accession":[]},"is_claimable":false,"name":"Risk of hip/femur fractures during the initiation period of α-adrenoceptor blocker therapy among elderly males: a self-controlled case series study.","description":"<h4>Aims</h4>This study aimed to evaluate the risk of hip/femur fractures during the initiation period of α-adrenoceptor blocker therapy using the National Health Insurance claims database, Taiwan, with a self-controlled case series design.<h4>Methods</h4>All male beneficiaries aged over 50 years as of 2007, who were incident users of α-adrenoceptor blockers and also had a diagnosis of hip/femur fracture within the 2007-2009 study period were identified. The first day when the α-adrenoceptor blocker was prescribed was set as the index date. We partitioned the initial 21 day period following the index date as the post-exposure risk period 1, days 22-60 after the index date as the post-exposure risk period 2, the 21 day period prior to the index date as the pre-exposure risk period 1 and day","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Nov","modification":"2025-04-06T19:45:31.106Z","creation":"2019-03-27T02:01:14Z"},"accession":"S-EPMC4631193","cross_references":{"pubmed":["25924025"],"doi":["10.1111/bcp.12671"]}}