{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(11)"],"submitter":["Watanabe M"],"pubmed_abstract":["This study aimed to investigate the effects of particulate matter (PM) on pulmonary function in schoolchildren, as well as the relationships of these effects with interleukin-8. Morning peak expiratory flow (PEF) was measured daily in 399 children during April-May 2012, and in 384 of these children during March-May 2013. PEF's association with the daily levels of suspended particulate matter (SPM) and PM < 2.5 mm (PM2.5) was estimated using a linear mixed model. Interleukin-8 promoter activity was assessed in THP-G8 cells stimulated by fallen PM collected at Tottori University Hospital during four periods (two in 2012 and two in 2013). An increase of 14.0 mg/m³ in SPM led to PEF changes of -2.16 L/min in 2012 and -0.81 L/min in 2013, respectively. An increment of 10.7 mg/m³ in PM2.5 was as"],"journal":["International journal of environmental research and public health"],"pagination":["14229-43"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4661643"],"repository":["biostudies-literature"],"pubmed_title":["Variation in the Effect of Particulate Matter on Pulmonary Function in Schoolchildren in Western Japan and Its Relation with Interleukin-8."],"pmcid":["PMC4661643"],"pubmed_authors":["Saito R","Kimura Y","Noma H","Kurai J","Kitano H","Watanabe M","Shimizu E","Aiba S","Sano H","Oshimura M"],"additional_accession":[]},"is_claimable":false,"name":"Variation in the Effect of Particulate Matter on Pulmonary Function in Schoolchildren in Western Japan and Its Relation with Interleukin-8.","description":"This study aimed to investigate the effects of particulate matter (PM) on pulmonary function in schoolchildren, as well as the relationships of these effects with interleukin-8. Morning peak expiratory flow (PEF) was measured daily in 399 children during April-May 2012, and in 384 of these children during March-May 2013. PEF's association with the daily levels of suspended particulate matter (SPM) and PM < 2.5 mm (PM2.5) was estimated using a linear mixed model. Interleukin-8 promoter activity was assessed in THP-G8 cells stimulated by fallen PM collected at Tottori University Hospital during four periods (two in 2012 and two in 2013). An increase of 14.0 mg/m³ in SPM led to PEF changes of -2.16 L/min in 2012 and -0.81 L/min in 2013, respectively. An increment of 10.7 mg/m³ in PM2.5 was as","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Nov","modification":"2025-04-19T03:01:54.919Z","creation":"2019-03-27T02:02:50Z"},"accession":"S-EPMC4661643","cross_references":{"pubmed":["26569272"],"doi":["10.3390/ijerph121114229"]}}