{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Doycheva I"],"funding":["NCATS NIH HHS","NIDDK NIH HHS","John A. Hartford Foundation","NIH"],"pagination":["83-95"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4673036"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["43(1)"],"pubmed_abstract":["<h4>Background</h4>Current guidelines do not recommend screening for non-alcoholic fatty liver disease (NAFLD) or advanced fibrosis. Patients with type 2 diabetes mellitus (T2DM) are known to be at increased risk for NAFLD and advanced fibrosis.<h4>Aim</h4>To assess the feasibility in diabetics in a primary care setting of screening for NAFLD and advanced fibrosis, by using non-invasive magnetic resonance imaging (MRI) to estimate the hepatic proton density fat fraction (MRI-PDFF) and magnetic resonance elastography (MRE) to estimate hepatic stiffness.<h4>Methods</h4>We performed a cross-sectional analysis of a prospective study that included 100 (53% men) consecutively enrolled diabetics who did not have any other aetiology of liver disease. All patients underwent a standardised research "],"journal":["Alimentary pharmacology & therapeutics"],"pubmed_title":["Non-invasive screening of diabetics in primary care for NAFLD and advanced fibrosis by MRI and MRE."],"pmcid":["PMC4673036"],"funding_grant_id":["K23 DK090303","K23-DK090303","5TL1TR000098‐05","TL1 TR000098","5TL1TR000098-05","R01 DK106419"],"pubmed_authors":["Bettencourt R","Doycheva I","Costa EA","Loomba R","Cui J","Hofflich H","Nguyen P","Brouha S","Sirlin CB","Hooker J"],"additional_accession":[]},"is_claimable":false,"name":"Non-invasive screening of diabetics in primary care for NAFLD and advanced fibrosis by MRI and MRE.","description":"<h4>Background</h4>Current guidelines do not recommend screening for non-alcoholic fatty liver disease (NAFLD) or advanced fibrosis. Patients with type 2 diabetes mellitus (T2DM) are known to be at increased risk for NAFLD and advanced fibrosis.<h4>Aim</h4>To assess the feasibility in diabetics in a primary care setting of screening for NAFLD and advanced fibrosis, by using non-invasive magnetic resonance imaging (MRI) to estimate the hepatic proton density fat fraction (MRI-PDFF) and magnetic resonance elastography (MRE) to estimate hepatic stiffness.<h4>Methods</h4>We performed a cross-sectional analysis of a prospective study that included 100 (53% men) consecutively enrolled diabetics who did not have any other aetiology of liver disease. All patients underwent a standardised research ","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Jan","modification":"2025-04-04T22:29:43.208Z","creation":"2019-03-27T02:04:48Z"},"accession":"S-EPMC4673036","cross_references":{"pubmed":["26369383"],"doi":["10.1111/apt.13405"]}}