biostudies-literatureDoycheva INCATS NIH HHSNIDDK NIH HHSJohn A. Hartford FoundationNIH83-95https://www.ebi.ac.uk/biostudies/studies/S-EPMC4673036biostudies-literatureUnknown43(1)<h4>Background</h4>Current guidelines do not recommend screening for non-alcoholic fatty liver disease (NAFLD) or advanced fibrosis. Patients with type 2 diabetes mellitus (T2DM) are known to be at increased risk for NAFLD and advanced fibrosis.<h4>Aim</h4>To assess the feasibility in diabetics in a primary care setting of screening for NAFLD and advanced fibrosis, by using non-invasive magnetic resonance imaging (MRI) to estimate the hepatic proton density fat fraction (MRI-PDFF) and magnetic resonance elastography (MRE) to estimate hepatic stiffness.<h4>Methods</h4>We performed a cross-sectional analysis of a prospective study that included 100 (53% men) consecutively enrolled diabetics who did not have any other aetiology of liver disease. All patients underwent a standardised research Alimentary pharmacology & therapeuticsNon-invasive screening of diabetics in primary care for NAFLD and advanced fibrosis by MRI and MRE.PMC4673036K23 DK090303K23-DK0903035TL1TR000098‐05TL1 TR0000985TL1TR000098-05R01 DK106419Bettencourt RDoycheva ICosta EALoomba RCui JHofflich HNguyen PBrouha SSirlin CBHooker JfalseNon-invasive screening of diabetics in primary care for NAFLD and advanced fibrosis by MRI and MRE.<h4>Background</h4>Current guidelines do not recommend screening for non-alcoholic fatty liver disease (NAFLD) or advanced fibrosis. Patients with type 2 diabetes mellitus (T2DM) are known to be at increased risk for NAFLD and advanced fibrosis.<h4>Aim</h4>To assess the feasibility in diabetics in a primary care setting of screening for NAFLD and advanced fibrosis, by using non-invasive magnetic resonance imaging (MRI) to estimate the hepatic proton density fat fraction (MRI-PDFF) and magnetic resonance elastography (MRE) to estimate hepatic stiffness.<h4>Methods</h4>We performed a cross-sectional analysis of a prospective study that included 100 (53% men) consecutively enrolled diabetics who did not have any other aetiology of liver disease. All patients underwent a standardised research 2016-01-01T00:00:00Z2016 Jan2025-04-04T22:29:43.208Z2019-03-27T02:04:48ZS-EPMC46730362636938310.1111/apt.13405