{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5"],"submitter":["Lin X"],"pubmed_abstract":["The brown plant hopper is one of the most destructive known pests of rice. We studied the roles of the JH receptor Met and the downstream transcription factor Kr-h1 in ovariole development and egg maturation. The predicted Met protein in N. lugens (NlMet) contained 517 amino acids. qRT-PCR showed that NlMet was expressed in all tissues and that the highest expression occurred in the embryonic stage. In NlMet- or NlKr-h1-silenced female adults, ovarian development varied significantly, whereas the numbers of ovarioles were less variable in those injected with dsRNA targeting NlMet, NlKrh-1 or both NlMet and NlKr-h1. In females injected with dsNlKr-h1 or with dsNlMet in combination with dsNlKr-h1 dsRNA, the preoviposition period was prolonged, whereas the females injected with NlMet dsRNA sh"],"journal":["Scientific reports"],"pagination":["18064"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4677288"],"repository":["biostudies-literature"],"pubmed_title":["Methoprene-tolerant (Met) and Krupple-homologue 1 (Kr-h1) are required for ovariole development and egg maturation in the brown plant hopper."],"pmcid":["PMC4677288"],"pubmed_authors":["Yao Y","Wang B","Lin X"],"additional_accession":[]},"is_claimable":false,"name":"Methoprene-tolerant (Met) and Krupple-homologue 1 (Kr-h1) are required for ovariole development and egg maturation in the brown plant hopper.","description":"The brown plant hopper is one of the most destructive known pests of rice. We studied the roles of the JH receptor Met and the downstream transcription factor Kr-h1 in ovariole development and egg maturation. The predicted Met protein in N. lugens (NlMet) contained 517 amino acids. qRT-PCR showed that NlMet was expressed in all tissues and that the highest expression occurred in the embryonic stage. In NlMet- or NlKr-h1-silenced female adults, ovarian development varied significantly, whereas the numbers of ovarioles were less variable in those injected with dsRNA targeting NlMet, NlKrh-1 or both NlMet and NlKr-h1. In females injected with dsNlKr-h1 or with dsNlMet in combination with dsNlKr-h1 dsRNA, the preoviposition period was prolonged, whereas the females injected with NlMet dsRNA sh","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Dec","modification":"2026-05-05T20:26:19.805Z","creation":"2025-05-29T22:30:04.207Z"},"accession":"S-EPMC4677288","cross_references":{"pubmed":["26658174"],"doi":["10.1038/srep18064"]}}