biostudies-literatureUnknown6Mizutani TScientific Research (B)Grant-in-Aid for Challenging Exploratory ResearchScientific Research on Innovative AreasThis data article describes cellular dynamics, such as migration speed and mobility of the cytoskeletal protein, of wild-type human fibroblast cells and cells with a modified adeno-associated virus integration site 1 (AAVS1) locus on human chromosome 19. Insertion of exogenous gene into the AAVS1 locus has been conducted in recent biological researches. Previously, our data showed that the AAVS1-modification changes cellular contractile force (Mizutani et al., 2015 [1]). To assess if this AAVS1-modification affects cell migration, we compared cellular migration speed and turnover of cytoskeletal protein in human fibroblasts and fibroblasts with a green fluorescent protein gene knocked-in at the AAVS1 locus in this data article. Cell nuclei were stained and changes in their position attribuData in brief793-8https://www.ebi.ac.uk/biostudies/studies/S-EPMC4749938biostudies-literatureData set for comparison of cellular dynamics between human AAVS1 locus-modified and wild-type cells.PMC4749938Kawabata KMizutani THaga HfalseData set for comparison of cellular dynamics between human AAVS1 locus-modified and wild-type cells.This data article describes cellular dynamics, such as migration speed and mobility of the cytoskeletal protein, of wild-type human fibroblast cells and cells with a modified adeno-associated virus integration site 1 (AAVS1) locus on human chromosome 19. Insertion of exogenous gene into the AAVS1 locus has been conducted in recent biological researches. Previously, our data showed that the AAVS1-modification changes cellular contractile force (Mizutani et al., 2015 [1]). To assess if this AAVS1-modification affects cell migration, we compared cellular migration speed and turnover of cytoskeletal protein in human fibroblasts and fibroblasts with a green fluorescent protein gene knocked-in at the AAVS1 locus in this data article. Cell nuclei were stained and changes in their position attribu2016-01-01T00:00:00Z2016 Mar2026-05-01T01:07:28.914Z2019-03-27T02:08:55ZS-EPMC47499382693744910.1016/j.dib.2015.12.053