{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Faraj C"],"funding":["Medical Research Council"],"pagination":["679-685"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4775907"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["94(3)"],"pubmed_abstract":["Cutaneous leishmaniasis (CL) remains an important public health problem in Morocco. A cluster-randomized trial was conducted with the following three study arms: 1) long-lasting insecticide-treated nets (LLINs) plus standard of care environmental management (SoC-EM), 2) indoor residual spraying (IRS) with α-cypermethrin plus SoC-EM, and 3) SoC-EM alone. Incidence of new CL cases by passive and active case detection, sandfly abundance, and cost and cost-effectiveness was compared between study arms over 5 years. Incidence of CL and sandfly abundance were significantly lower in the IRS arm compared with SoC-EM (CL incidence rate ratio = 0.32, 95% confidence interval [CI] = 0.15-0.69, P = 0.005 and sandfly abundance ratio = 0.39, 95% CI = 0.18-0.85, P = 0.022). Reductions in the LLIN arm of t"],"journal":["The American journal of tropical medicine and hygiene"],"pubmed_title":["Effectiveness and Cost of Insecticide-Treated Bed Nets and Indoor Residual Spraying for the Control of Cutaneous Leishmaniasis: A Cluster-Randomized Control Trial in Morocco."],"pmcid":["PMC4775907"],"funding_grant_id":["MR/K012126/1"],"pubmed_authors":["Kaddaf M","Kleinschmidt I","Wahabi R","Ameur B","Adlaoui EB","El Idrissi AL","Yukich J","Mnzava AP","Faraj C"],"additional_accession":[]},"is_claimable":false,"name":"Effectiveness and Cost of Insecticide-Treated Bed Nets and Indoor Residual Spraying for the Control of Cutaneous Leishmaniasis: A Cluster-Randomized Control Trial in Morocco.","description":"Cutaneous leishmaniasis (CL) remains an important public health problem in Morocco. A cluster-randomized trial was conducted with the following three study arms: 1) long-lasting insecticide-treated nets (LLINs) plus standard of care environmental management (SoC-EM), 2) indoor residual spraying (IRS) with α-cypermethrin plus SoC-EM, and 3) SoC-EM alone. Incidence of new CL cases by passive and active case detection, sandfly abundance, and cost and cost-effectiveness was compared between study arms over 5 years. Incidence of CL and sandfly abundance were significantly lower in the IRS arm compared with SoC-EM (CL incidence rate ratio = 0.32, 95% confidence interval [CI] = 0.15-0.69, P = 0.005 and sandfly abundance ratio = 0.39, 95% CI = 0.18-0.85, P = 0.022). Reductions in the LLIN arm of t","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Mar","modification":"2025-04-04T10:27:13.304Z","creation":"2019-03-27T02:10:21Z"},"accession":"S-EPMC4775907","cross_references":{"pubmed":["26811431"],"doi":["10.4269/ajtmh.14-0510"]}}