{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sleeper LA"],"funding":["NHLBI NIH HHS"],"pagination":["173-80.e1-4"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4790092"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["170"],"pubmed_abstract":["<h4>Objectives</h4>To measure the health-related quality of life (HRQOL) and functional status of children with cardiomyopathy and to determine whether they are correlated with sociodemographics, cardiac status, and clinical outcomes.<h4>Study design</h4>Parents of children in the Pediatric Cardiomyopathy Registry completed the Child Health Questionnaire (CHQ; age ≥ 5 years) and Functional Status II (Revised) (age ≤ 18 years) instruments. Linear and Cox regressions were used to examine hypothesized associations with HRQOL.<h4>Results</h4>The 355 children evaluated at ≥ 5 years (median 8.6 years) had lower functioning (CHQ Physical and Psychosocial Summary Scores 41.7 ± 14.4 and 47.8 ± 10.7) than that of healthy historical controls. The most extreme CHQ domain score, Parental Impact-Emotion"],"journal":["The Journal of pediatrics"],"pubmed_title":["Health-Related Quality of Life and Functional Status Are Associated with Cardiac Status and Clinical Outcome in Children with Cardiomyopathy."],"pmcid":["PMC4790092"],"funding_grant_id":["R01 HL053392","R01 HL HL53392"],"pubmed_authors":["Everitt M","Addonizio L","Epstein S","Rusconi P","Korsin R","Kaufman B","McDonald M","Noonan K","Czachor J","Rees MA","Kantor P","Hill-Edgar A","Benson L","Pophali N","Lowe A","Gurell M","Jefferies JL","O'Brien R","Grenier MA","Steeg C","Shaddy R","Giantris A","Lewis K","Buzzard C","Muto E","Cuniberti L","Shaikh S","Canter C","Pediatric Cardiomyopathy Registry Investigators","Fountain D","Carron H","Miller TL","Messere J","Pahl E","Lu M","Rauch E","Gidding S","Gilroy L","Cafferata L","Wilk D","Dauphin D","Lemler MS","Chrisant M","Cianfrini C","Tighe F","Lemler M","Clunie S","Wilkinson JD","Keesler M","Colan S","Sleeper LA","Lurie P","Fixler D","Tamer D","Colan SD","Wolfe G","Newman A","McKee T","Truesdell S","Sullivan W","Alvarez JA","Osganian S","Alvarez J","Hsu D","Webber S","Orfaly R","Arsenault P","Exil V","Sleeper L","Meloche M","Towbin J","Rossetti R","Orav EJ","Schiavoni L","Strauss A","Rossano J","Lipshultz SE","McCoy K","Rossetti L","Cox G","Rodgers S","Towbin JA"],"additional_accession":[]},"is_claimable":false,"name":"Health-Related Quality of Life and Functional Status Are Associated with Cardiac Status and Clinical Outcome in Children with Cardiomyopathy.","description":"<h4>Objectives</h4>To measure the health-related quality of life (HRQOL) and functional status of children with cardiomyopathy and to determine whether they are correlated with sociodemographics, cardiac status, and clinical outcomes.<h4>Study design</h4>Parents of children in the Pediatric Cardiomyopathy Registry completed the Child Health Questionnaire (CHQ; age ≥ 5 years) and Functional Status II (Revised) (age ≤ 18 years) instruments. Linear and Cox regressions were used to examine hypothesized associations with HRQOL.<h4>Results</h4>The 355 children evaluated at ≥ 5 years (median 8.6 years) had lower functioning (CHQ Physical and Psychosocial Summary Scores 41.7 ± 14.4 and 47.8 ± 10.7) than that of healthy historical controls. The most extreme CHQ domain score, Parental Impact-Emotion","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Mar","modification":"2025-04-20T02:40:28.749Z","creation":"2019-03-27T02:11:02Z"},"accession":"S-EPMC4790092","cross_references":{"pubmed":["26725459"],"doi":["10.1016/j.jpeds.2015.10.004"]}}