{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yadlapati R"],"funding":["NIDDK NIH HHS","AHRQ HHS"],"pagination":["535-542.e2"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4799733"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(4)"],"pubmed_abstract":["Background & aims
It has been a challenge to confirm the association between laryngeal symptoms and physiological reflux disease. We examined the ability of oropharyngeal pH tests (with the Restech Dx-pH system) and salivary pepsin tests (with Peptest) to discriminate between asymptomatic volunteers (controls) and subjects with a combination of laryngeal and reflux symptoms (laryngeal ± reflux).Methods
We performed a physician-blinded prospective cohort study of 59 subjects at a single academic institution. Adult volunteers were recruited and separated into 3 groups on the basis of GerdQ and Reflux Symptom Index scores: controls (n = 20), laryngeal symptoms (n = 20), or laryngeal + reflux symptoms (n = 19). Subjects underwent laryngoscopy and oropharyngeal pH tests and subm"],"journal":["Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association"],"pubmed_title":["Abilities of Oropharyngeal pH Tests and Salivary Pepsin Analysis to Discriminate Between Asymptomatic Volunteers and Subjects With Symptoms of Laryngeal Irritation."],"pmcid":["PMC4799733"],"funding_grant_id":["T32DK101363-02","K12 HS023011","T32 DK101363"],"pubmed_authors":["Lidder AK","Ellenbogen M","Adkins C","Tan BK","Jaiyeola DM","Yadlapati R","Smith SS","Price CP","Pandolfino JE","Shabeeb N","Bove M","Agrawal N","Gawron AJ"],"additional_accession":[]},"is_claimable":false,"name":"Abilities of Oropharyngeal pH Tests and Salivary Pepsin Analysis to Discriminate Between Asymptomatic Volunteers and Subjects With Symptoms of Laryngeal Irritation.","description":"Background & aims
It has been a challenge to confirm the association between laryngeal symptoms and physiological reflux disease. We examined the ability of oropharyngeal pH tests (with the Restech Dx-pH system) and salivary pepsin tests (with Peptest) to discriminate between asymptomatic volunteers (controls) and subjects with a combination of laryngeal and reflux symptoms (laryngeal ± reflux).Methods
We performed a physician-blinded prospective cohort study of 59 subjects at a single academic institution. Adult volunteers were recruited and separated into 3 groups on the basis of GerdQ and Reflux Symptom Index scores: controls (n = 20), laryngeal symptoms (n = 20), or laryngeal + reflux symptoms (n = 19). Subjects underwent laryngoscopy and oropharyngeal pH tests and subm","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Apr","modification":"2025-04-22T12:04:28.548Z","creation":"2019-03-27T02:11:27Z"},"accession":"S-EPMC4799733","cross_references":{"pubmed":["26689899"],"doi":["10.1016/j.cgh.2015.11.017"]}}