{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(3)"],"submitter":["Tosello F"],"pubmed_abstract":["<h4>Introduction</h4>Current evidence suggests that aortic blood pressure has a superior prognostic value with respect to brachial pressure for cardiovascular events, but direct measurement is not feasible in daily clinical practice.<h4>Aim</h4>The aim of the present study is the clinical validation of a multiscale mathematical model for non-invasive appraisal of central blood pressure from subject-specific characteristics.<h4>Methods</h4>A total of 51 young male were selected for the present study. Aortic systolic and diastolic pressure were estimated with a mathematical model and were compared to the most-used non-invasive validated technique (SphygmoCor device, AtCor Medical, Australia). SphygmoCor was calibrated through diastolic and systolic brachial pressure obtained with a sphygmoma"],"journal":["PloS one"],"pagination":["e0151523"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4806836"],"repository":["biostudies-literature"],"pubmed_title":["Central Pressure Appraisal: Clinical Validation of a Subject-Specific Mathematical Model."],"pmcid":["PMC4806836"],"pubmed_authors":["Veglio F","Milan A","Guala A","Leone D","Bruno G","Ridolfi L","Tosello F","Camporeale C"],"additional_accession":[]},"is_claimable":false,"name":"Central Pressure Appraisal: Clinical Validation of a Subject-Specific Mathematical Model.","description":"<h4>Introduction</h4>Current evidence suggests that aortic blood pressure has a superior prognostic value with respect to brachial pressure for cardiovascular events, but direct measurement is not feasible in daily clinical practice.<h4>Aim</h4>The aim of the present study is the clinical validation of a multiscale mathematical model for non-invasive appraisal of central blood pressure from subject-specific characteristics.<h4>Methods</h4>A total of 51 young male were selected for the present study. Aortic systolic and diastolic pressure were estimated with a mathematical model and were compared to the most-used non-invasive validated technique (SphygmoCor device, AtCor Medical, Australia). SphygmoCor was calibrated through diastolic and systolic brachial pressure obtained with a sphygmoma","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016","modification":"2025-04-04T20:13:00.506Z","creation":"2019-03-26T22:53:40Z"},"accession":"S-EPMC4806836","cross_references":{"pubmed":["27010562"],"doi":["10.1371/journal.pone.0151523"]}}