{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Grzes M"],"funding":["Ministry of Science and Technology"],"pagination":["381-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4831998"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["43(5)"],"pubmed_abstract":["Fat content and fatty acid (FA) profile influence meat quality in pigs. These parameters are important for consumers due to their preferences for healthy, high quality meat. The aim of this study was searching for polymorphisms and transcript levels of two positional and functional candidate genes, FASN and INSIG2, encoding proteins which take part in lipid metabolism. The molecular findings were analyzed in relation to fatness traits. Pigs of four commercial breeds were included: Polish Landrace (PL), Polish Large White (PLW), Duroc and Pietrain. DNA sequencing, 5'RACE technique and real time PCR and association analysis were applied. In total, 20 polymorphisms in 5'-flanking, 5'UTR and 3'UTR regions of FASN (12 novel polymorphisms) and INSIG2 (seven novel ones and one known) genes were f"],"journal":["Molecular biology reports"],"pubmed_title":["Pig fatness in relation to FASN and INSIG2 genes polymorphism and their transcript level."],"pmcid":["PMC4831998"],"funding_grant_id":["N311 288936"],"pubmed_authors":["Switonski M","Grzes M","Rzewuska K","Sadkowski S","Szydlowski M"],"additional_accession":[]},"is_claimable":false,"name":"Pig fatness in relation to FASN and INSIG2 genes polymorphism and their transcript level.","description":"Fat content and fatty acid (FA) profile influence meat quality in pigs. These parameters are important for consumers due to their preferences for healthy, high quality meat. The aim of this study was searching for polymorphisms and transcript levels of two positional and functional candidate genes, FASN and INSIG2, encoding proteins which take part in lipid metabolism. The molecular findings were analyzed in relation to fatness traits. Pigs of four commercial breeds were included: Polish Landrace (PL), Polish Large White (PLW), Duroc and Pietrain. DNA sequencing, 5'RACE technique and real time PCR and association analysis were applied. In total, 20 polymorphisms in 5'-flanking, 5'UTR and 3'UTR regions of FASN (12 novel polymorphisms) and INSIG2 (seven novel ones and one known) genes were f","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 May","modification":"2026-04-12T23:49:44.09Z","creation":"2019-03-27T02:11:32Z"},"accession":"S-EPMC4831998","cross_references":{"pubmed":["26965892"],"doi":["10.1007/s11033-016-3969-z"]}}