{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yanik EL"],"funding":["NCCDPHP CDC HHS","NCI NIH HHS"],"pagination":["1495-504"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4849829"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(5)"],"pubmed_abstract":["Among patients with ESRD, cancer risk is affected by kidney dysfunction and by immunosuppression after transplant. Assessing patterns across periods of dialysis and kidney transplantation may inform cancer etiology. We evaluated 202,195 kidney transplant candidates and recipients from a linkage between the Scientific Registry of Transplant Recipients and cancer registries, and compared incidence in kidney function intervals (time with a transplant) with incidence in nonfunction intervals (waitlist or time after transplant failure), adjusting for demographic factors. Incidence of infection-related and immune-related cancer was higher during kidney function intervals than during nonfunction intervals. Incidence was most elevated for Kaposi sarcoma (hazard ratio [HR], 9.1; 95% confidence inte"],"journal":["Journal of the American Society of Nephrology : JASN"],"pubmed_title":["Variation in Cancer Incidence among Patients with ESRD during Kidney Function and Nonfunction Intervals."],"pmcid":["PMC4849829"],"funding_grant_id":["U58 DP003879","U58 DP003921","U58 DP000832","U58 DP003931","U58 DP000824","HHSN261201300021C","HHSN261201000035I","N01PC35137","U58 DP003875","N01PC35139","HHSN261201000034C","U58 DP003883","HHSN261201000035C","HHSN261201000024C","HHSN261201000036C","HHSN261201000026C","N01PC35143","HHSN261201000037C","N01PC35142","U58 DP000848","U58 DP000807"],"pubmed_authors":["Clarke CA","Snyder JJ","Pfeiffer RM","Engels EA","Yanik EL"],"additional_accession":[]},"is_claimable":false,"name":"Variation in Cancer Incidence among Patients with ESRD during Kidney Function and Nonfunction Intervals.","description":"Among patients with ESRD, cancer risk is affected by kidney dysfunction and by immunosuppression after transplant. Assessing patterns across periods of dialysis and kidney transplantation may inform cancer etiology. We evaluated 202,195 kidney transplant candidates and recipients from a linkage between the Scientific Registry of Transplant Recipients and cancer registries, and compared incidence in kidney function intervals (time with a transplant) with incidence in nonfunction intervals (waitlist or time after transplant failure), adjusting for demographic factors. Incidence of infection-related and immune-related cancer was higher during kidney function intervals than during nonfunction intervals. Incidence was most elevated for Kaposi sarcoma (hazard ratio [HR], 9.1; 95% confidence inte","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 May","modification":"2025-04-04T07:30:38.114Z","creation":"2019-03-27T02:12:40Z"},"accession":"S-EPMC4849829","cross_references":{"pubmed":["26563384"],"doi":["10.1681/asn.2015040373","10.1681/ASN.2015040373"]}}