{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["37(19)"],"submitter":["Riegger J"],"pubmed_abstract":["<h4>Background</h4>Stent thrombosis (ST) is a rare but serious complication following percutaneous coronary intervention. Analysis of thrombus composition from patients undergoing catheter thrombectomy may provide important insights into the pathological processes leading to thrombus formation. We performed a large-scale multicentre study to evaluate thrombus specimens in patients with ST across Europe.<h4>Methods</h4>Patients presenting with ST and undergoing thrombus aspiration were eligible for inclusion. Thrombus collection was performed according to a standardized protocol and specimens were analysed histologically at a core laboratory. Serial tissue cross sections were stained with haematoxylin-eosin (H&E), Carstairs and Luna. Immunohistochemistry was performed to identify leukocyte "],"journal":["European heart journal"],"pagination":["1538-49"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4872283"],"repository":["biostudies-literature"],"pubmed_title":["Histopathological evaluation of thrombus in patients presenting with stent thrombosis. A multicenter European study: a report of the prevention of late stent thrombosis by an interdisciplinary global European effort consortium."],"pmcid":["PMC4872283"],"pubmed_authors":["Steg PG","Ten Berg J","Gershlick AH","Opinaldo S","Bernelli C","Adriaenssens T","Schulz C","Suresh V","Vogelsang A","Godschalk TC","Mangin P","Rzeszutko L","Zahman A","Heestermans AA","Koppara T","Oldroyd K","Jhagroe DA","Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Investigators","Barbato E","Kennerknecht E","Byrne RA","Gratz M","Cuesta J","De Cock D","Dens J","Hill J","Kastrati A","Cotton J","Gershlick A","Winkens MH","Konrad I","Tada T","Sinnaeve P","Gerber R","Berry C","Wykrzykowska JJ","Steigerwald K","Chausson M","Chandraratne S","Valina C","McEntegart M","Olivier V","Letourneur D","Routledge H","Sirbu V","Abergel H","Neumann FJ","Kerch G","Ntziachristos V","Shannon J","Buysschaert I","Titova A","Coccato M","Amoroso G","Feldman L","Dewilde WJ","Guagliumi G","Kelly D","Ten Berg JM","Alfonso F","Wojdyla R","Feldman LJ","Philippi V","Rzany A","Riegger J","Zasada W","Malik N","Dudek D","Goodall AH","Curzen N","Massberg S","Rosenthal A","Hetherington S","Medina M","Desmet W","Xhepa E","Jandrot-Perrus M","Joner M","Vermeersch P","Roques C","Komukai K","Trenk D","Gautier S"],"additional_accession":[]},"is_claimable":false,"name":"Histopathological evaluation of thrombus in patients presenting with stent thrombosis. A multicenter European study: a report of the prevention of late stent thrombosis by an interdisciplinary global European effort consortium.","description":"<h4>Background</h4>Stent thrombosis (ST) is a rare but serious complication following percutaneous coronary intervention. Analysis of thrombus composition from patients undergoing catheter thrombectomy may provide important insights into the pathological processes leading to thrombus formation. We performed a large-scale multicentre study to evaluate thrombus specimens in patients with ST across Europe.<h4>Methods</h4>Patients presenting with ST and undergoing thrombus aspiration were eligible for inclusion. Thrombus collection was performed according to a standardized protocol and specimens were analysed histologically at a core laboratory. Serial tissue cross sections were stained with haematoxylin-eosin (H&E), Carstairs and Luna. Immunohistochemistry was performed to identify leukocyte ","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 May","modification":"2026-04-08T16:05:38.988Z","creation":"2026-04-08T05:59:06.581Z"},"accession":"S-EPMC4872283","cross_references":{"pubmed":["26761950"],"doi":["10.1093/eurheartj/ehv419"]}}