biostudies-literatureMoslehi RU.S. Department of DefenseSusan G. Komen for the CureNCI NIH HHS334https://www.ebi.ac.uk/biostudies/studies/S-EPMC4881056biostudies-literatureUnknown16<h4>Background</h4>To assess the importance of heredity in the etiology of inflammatory breast cancer (IBC), we compared IBC patients to several carefully chosen comparison groups with respect to the prevalence of first-degree family history of breast cancer.<h4>Methods</h4>IBC cases (n = 141) were compared to non-inflammatory breast cancer cases (n = 178) ascertained through George Washington University (GWU) with respect to the prevalence of first-degree family history of breast cancer and selected environmental/lifestyle risk factors for breast cancer. Similar comparisons were conducted with subjects from three case-control studies: breast cancer cases (n = 1145) and unaffected controls (n = 1142) from the Cancer Genetic Markers of Susceptibility (CGEMS) study, breast cancer cases (n = BMC cancerImportance of hereditary and selected environmental risk factors in the etiology of inflammatory breast cancer: a case-comparison study.PMC4881056BCTR00-000510R25 CA094061T32 CA094061BC009014Moslehi RLevine PHFreedman EZeinomar NVeneroso CfalseImportance of hereditary and selected environmental risk factors in the etiology of inflammatory breast cancer: a case-comparison study.<h4>Background</h4>To assess the importance of heredity in the etiology of inflammatory breast cancer (IBC), we compared IBC patients to several carefully chosen comparison groups with respect to the prevalence of first-degree family history of breast cancer.<h4>Methods</h4>IBC cases (n = 141) were compared to non-inflammatory breast cancer cases (n = 178) ascertained through George Washington University (GWU) with respect to the prevalence of first-degree family history of breast cancer and selected environmental/lifestyle risk factors for breast cancer. Similar comparisons were conducted with subjects from three case-control studies: breast cancer cases (n = 1145) and unaffected controls (n = 1142) from the Cancer Genetic Markers of Susceptibility (CGEMS) study, breast cancer cases (n = 2016-01-01T00:00:00Z2016 May2025-06-01T12:01:33.253Z2025-06-01T12:01:33.253ZS-EPMC48810562722968710.1186/s12885-016-2369-z