{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Black DM"],"funding":["Welch-Foundation","NIMHD NIH HHS","Division of Materials Research","National Institute on Minority Health and Health Disparities"],"pagination":["10679-87"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4886723"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["118(45)"],"pubmed_abstract":["Gas-phase reactions of larger gold clusters are poorly known because generation of the intact parent species for mass spectrometric analysis remains quite challenging. Herein we report in-source collision-induced dissociation (CID) results for the monolayer protected clusters (MPCs) Au144(SR)60 and Au130(SR)50, where R- = PhCH2CH2-, in a Bruker micrOTOF time-of-flight mass spectrometer. A sample mixture of the two clusters was introduced into the mass spectrometer by positive mode electrospray ionization. Standard source conditions were used to acquire a reference mass spectrum, exhibiting negligible fragmentation, and then the capillary-skimmer potential difference was increased to induce in-source CID within this low-pressure region (∼4 mbar). Remarkably, distinctive fragmentation patterns are observed for each MPC[3+] parent ion. An assignment of all the major dissociation products (ions and neutrals) is deduced and interpreted by using the distinguishing characteristics in the standard structure-models for the respective MPCs. Also, we propose a ring-forming elimination mechanism to explain R-H neutral loss, as separate from the channels leading to RS-SR or (AuSR)4 neutrals."],"journal":["The journal of physical chemistry. A"],"pubmed_title":["Collision-induced dissociation of monolayer protected clusters Au144 and Au130 in an electrospray time-of-flight mass spectrometer."],"pmcid":["PMC4886723"],"funding_grant_id":["DMR 0934218","G12MD007591","G12 MD007591","AX-1857"],"pubmed_authors":["Black DM","Bhattarai N","Whetten RL","Bach SB"],"additional_accession":[]},"is_claimable":false,"name":"Collision-induced dissociation of monolayer protected clusters Au144 and Au130 in an electrospray time-of-flight mass spectrometer.","description":"Gas-phase reactions of larger gold clusters are poorly known because generation of the intact parent species for mass spectrometric analysis remains quite challenging. Herein we report in-source collision-induced dissociation (CID) results for the monolayer protected clusters (MPCs) Au144(SR)60 and Au130(SR)50, where R- = PhCH2CH2-, in a Bruker micrOTOF time-of-flight mass spectrometer. A sample mixture of the two clusters was introduced into the mass spectrometer by positive mode electrospray ionization. Standard source conditions were used to acquire a reference mass spectrum, exhibiting negligible fragmentation, and then the capillary-skimmer potential difference was increased to induce in-source CID within this low-pressure region (∼4 mbar). Remarkably, distinctive fragmentation patterns are observed for each MPC[3+] parent ion. An assignment of all the major dissociation products (ions and neutrals) is deduced and interpreted by using the distinguishing characteristics in the standard structure-models for the respective MPCs. Also, we propose a ring-forming elimination mechanism to explain R-H neutral loss, as separate from the channels leading to RS-SR or (AuSR)4 neutrals.","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Nov","modification":"2026-05-05T14:26:42.733Z","creation":"2019-03-27T02:14:51Z"},"accession":"S-EPMC4886723","cross_references":{"pubmed":["25317476"],"doi":["10.1021/jp508059j"]}}