biostudies-literatureUnknown16Fontanelli Sulekova L<h4>Background</h4>Human dirofilariosis is still a little known infection even in endemic areas. Dirofilariosis is zoonotic infection usually abortive in humans; instead, we report a very rare case (the 4th in the world), the first in Italy, in which at least two infective larvae became mature adults that mated and produced active microfilariae even though they did not reach peripheral blood.<h4>Case presentation</h4>A 30-year-old Italian woman presented with a transient oedematous swelling on the left abdominal wall with a creeping eruption followed by the occurrence of a subcutaneous nodular painless mass in the iliac region. One month later, a similar temporary swelling appeared on the contralateral inguinal region associated with intermittent joint discomfort in both knees. The patientBMC infectious diseases248https://www.ebi.ac.uk/biostudies/studies/S-EPMC4895828biostudies-literatureDirofilaria repens microfilariae from a human node fine-needle aspirate: a case report.PMC4895828Gabrielli SDe Angelis MMilardi GLDi Marco BTaliani GCancrini GFontanelli Sulekova LMagnani CfalseDirofilaria repens microfilariae from a human node fine-needle aspirate: a case report.<h4>Background</h4>Human dirofilariosis is still a little known infection even in endemic areas. Dirofilariosis is zoonotic infection usually abortive in humans; instead, we report a very rare case (the 4th in the world), the first in Italy, in which at least two infective larvae became mature adults that mated and produced active microfilariae even though they did not reach peripheral blood.<h4>Case presentation</h4>A 30-year-old Italian woman presented with a transient oedematous swelling on the left abdominal wall with a creeping eruption followed by the occurrence of a subcutaneous nodular painless mass in the iliac region. One month later, a similar temporary swelling appeared on the contralateral inguinal region associated with intermittent joint discomfort in both knees. The patient2016-01-01T00:00:00Z2016 Jun2026-06-14T03:32:40.885Z2019-06-06T15:54:56ZS-EPMC48958282726651210.1186/s12879-016-1582-3