{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lawson RA"],"funding":["Medical Research Council","Wellcome Trust","Parkinson's UK"],"pagination":["47-53"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4906150"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27"],"pubmed_abstract":["Introduction
Parkinson's disease dementia (PDD) is associated with poorer quality of life (QoL). Prior to the onset of PDD, many patients experience progressive cognitive impairment. There is a paucity of longitudinal studies investigating the effects of cognitive decline on QoL. This study aimed to determine the longitudinal impact of cognitive change on QoL in an incident PD cohort.Methods
Recently diagnosed patients with PD (n = 212) completed a schedule of neuropsychological assessments and QoL measures; these were repeated after 18 (n = 190) and 36 months (n = 158). Mild cognitive impairment (PD-MCI) was classified with reference to the Movement Disorder Society criteria. Principal component analysis was used to reduce 10 neuropsychological tests to three cognitive fac"],"journal":["Parkinsonism & related disorders"],"pubmed_title":["Cognitive decline and quality of life in incident Parkinson's disease: The role of attention."],"pmcid":["PMC4906150"],"funding_grant_id":["MC_U105597119","103838/Z/14/Z","J-0802"],"pubmed_authors":["Duncan GW","Khoo TK","ICICLE-PD study group","Breen DP","Williams-Gray CH","Taylor JP","Lawson RA","Collerton D","Burn DJ","Barker RA","Yarnall AJ"],"additional_accession":[]},"is_claimable":false,"name":"Cognitive decline and quality of life in incident Parkinson's disease: The role of attention.","description":"Introduction
Parkinson's disease dementia (PDD) is associated with poorer quality of life (QoL). Prior to the onset of PDD, many patients experience progressive cognitive impairment. There is a paucity of longitudinal studies investigating the effects of cognitive decline on QoL. This study aimed to determine the longitudinal impact of cognitive change on QoL in an incident PD cohort.Methods
Recently diagnosed patients with PD (n = 212) completed a schedule of neuropsychological assessments and QoL measures; these were repeated after 18 (n = 190) and 36 months (n = 158). Mild cognitive impairment (PD-MCI) was classified with reference to the Movement Disorder Society criteria. Principal component analysis was used to reduce 10 neuropsychological tests to three cognitive fac","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Jun","modification":"2025-04-19T23:17:44.202Z","creation":"2019-03-27T02:15:56Z"},"accession":"S-EPMC4906150","cross_references":{"pubmed":["27094482"],"doi":["10.1016/j.parkreldis.2016.04.009"]}}