{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5(2)"],"submitter":["Schafer C"],"funding":["Ministero dell′Istruzione, dell′Università e della Ricerca (PRIN project “InfoChem”)","Centre National de la Recherche Scientifique (CNRS)","Institute of Advanced Studies of the University of Bologna","University of Bologna","Université Paris Descartes, Sorbonne Paris Cité"],"pubmed_abstract":["The transport of substrates is one of the main tasks of biomolecular machines in living organisms. We report a synthetic small-molecule system designed to catch, displace, and release molecular cargo in solution under external control. The system consists of a bistable rotaxane that behaves as an acid-base controlled molecular shuttle, whose ring component bears a tether ending with a nitrile group. The latter can be coordinated to a ruthenium complex that acts as the load, and dissociated upon irradiation with visible light. The cargo loading/unloading and ring transfer/return processes are reversible and can be controlled independently. The robust coordination bond ensures that the cargo remains attached to the device while the transport takes place."],"journal":["ChemistryOpen"],"pagination":["120-4"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4906471"],"repository":["biostudies-literature"],"pubmed_title":["An Artificial Molecular Transporter."],"pmcid":["PMC4906471"],"pubmed_authors":["Schafer C","Colasson B","Credi A","Silvi S","La Rosa M","Ragazzon G"],"additional_accession":[]},"is_claimable":false,"name":"An Artificial Molecular Transporter.","description":"The transport of substrates is one of the main tasks of biomolecular machines in living organisms. We report a synthetic small-molecule system designed to catch, displace, and release molecular cargo in solution under external control. The system consists of a bistable rotaxane that behaves as an acid-base controlled molecular shuttle, whose ring component bears a tether ending with a nitrile group. The latter can be coordinated to a ruthenium complex that acts as the load, and dissociated upon irradiation with visible light. The cargo loading/unloading and ring transfer/return processes are reversible and can be controlled independently. The robust coordination bond ensures that the cargo remains attached to the device while the transport takes place.","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Apr","modification":"2025-04-19T23:19:06.799Z","creation":"2019-03-27T02:15:59Z"},"accession":"S-EPMC4906471","cross_references":{"pubmed":["27308223"],"doi":["10.1002/open.201500217"]}}