biostudies-literatureUnknown16(1)Masa JFSpanish Respiratory Foundation 2011 (FEPAR)<h4>Background</h4>Severe acidosis can cause noninvasive ventilation (NIV) failure in chronic obstructive pulmonary disease (COPD) patients with acute hypercapnic respiratory failure (AHRF). NIV is therefore contraindicated outside of intensive care units (ICUs) in these patients. Less is known about NIV failure in patients with acute cardiogenic pulmonary edema (ACPE) and obesity hypoventilation syndrome (OHS). Therefore, the objective of the present study was to compare NIV failure rates between patients with severe and non-severe acidosis admitted to a respiratory intermediate care unit (RICU) with AHRF resulting from ACPE, COPD or OHS.<h4>Methods</h4>We prospectively included acidotic patients admitted to seven RICUs, where they were provided NIV as an initial ventilatory support measuBMC pulmonary medicine97https://www.ebi.ac.uk/biostudies/studies/S-EPMC4937546biostudies-literatureNoninvasive ventilation for severely acidotic patients in respiratory intermediate care units : Precision medicine in intermediate care units.PMC4937546Utrabo IGomez-Mendieta MAGomez de Terreros JOrtega-Gonzalez AAnton APenacoba PZamora EEsteban CSegrelles GPina JAFarrero EJara-Palomares LMasa JFMartin-Vicente MJRodriguez-Jerez FBinimelis ASala EBarrot ESayas JRivas FJEgea CJPrats EFernandez-Alvarez RSanchez-Oro-Gomez RSerrano-Rebollo JCAburto MNunez BCatala RCebrian JJMendez LBenavides PSantiago-Recuerda AfalseNoninvasive ventilation for severely acidotic patients in respiratory intermediate care units : Precision medicine in intermediate care units.<h4>Background</h4>Severe acidosis can cause noninvasive ventilation (NIV) failure in chronic obstructive pulmonary disease (COPD) patients with acute hypercapnic respiratory failure (AHRF). NIV is therefore contraindicated outside of intensive care units (ICUs) in these patients. Less is known about NIV failure in patients with acute cardiogenic pulmonary edema (ACPE) and obesity hypoventilation syndrome (OHS). Therefore, the objective of the present study was to compare NIV failure rates between patients with severe and non-severe acidosis admitted to a respiratory intermediate care unit (RICU) with AHRF resulting from ACPE, COPD or OHS.<h4>Methods</h4>We prospectively included acidotic patients admitted to seven RICUs, where they were provided NIV as an initial ventilatory support measu2016-01-01T00:00:00Z2016 Jul2025-04-19T21:51:53.576Z2019-03-27T02:17:50ZS-EPMC49375462738754410.1186/s12890-016-0262-9