biostudies-literaturePark HAgriculture and Food Research Initiative EducationNICHD NIH HHSNebraska Beef CouncilGerber FoundationNational Cattlemen&apos;s Beef AssociationLiteracy Initiative Predoctoral FellowshipNIHUSDA National Institute of Food and AgricultureAmerican Egg Board/Egg Nutrition Center1537-45https://www.ebi.ac.uk/biostudies/studies/S-EPMC4958290biostudies-literatureUnknown146(8)<h4>Background</h4>The impact of the reproductive state on vitamin D metabolism and requirements is uncertain in part because of a lack of studies with controlled dietary intakes of vitamin D and related nutrients.<h4>Objective</h4>We aimed to quantify the impact of the reproductive state on a panel of vitamin D biomarkers among women of childbearing age consuming equivalent amounts of vitamin D and related nutrients.<h4>Methods</h4>Nested within a feeding study providing 2 doses of choline, healthy pregnant (26-29 wk gestation; n = 26), lactating (5 wk postpartum; n = 28), and control (nonpregnant/nonlactating; n = 21) women consumed a single amount of vitamin D (511 ± 48 IU/d: 311 ± 48 IU/d from diet and 200 IU/d as supplemental cholecalciferol) and related nutrients (1.6 ± 0.4 g Ca/d anThe Journal of nutritionVitamin D Metabolism Varies among Women in Different Reproductive States Consuming the Same Intakes of Vitamin D and Related Nutrients.PMC4958290R03 HD0808242016-67011-251741R03HD080824-01A11843-3882West AAPark HYan JPerry CAMalysheva OVBrannon PMJiang XCaudill MAMehta SfalseVitamin D Metabolism Varies among Women in Different Reproductive States Consuming the Same Intakes of Vitamin D and Related Nutrients.<h4>Background</h4>The impact of the reproductive state on vitamin D metabolism and requirements is uncertain in part because of a lack of studies with controlled dietary intakes of vitamin D and related nutrients.<h4>Objective</h4>We aimed to quantify the impact of the reproductive state on a panel of vitamin D biomarkers among women of childbearing age consuming equivalent amounts of vitamin D and related nutrients.<h4>Methods</h4>Nested within a feeding study providing 2 doses of choline, healthy pregnant (26-29 wk gestation; n = 26), lactating (5 wk postpartum; n = 28), and control (nonpregnant/nonlactating; n = 21) women consumed a single amount of vitamin D (511 ± 48 IU/d: 311 ± 48 IU/d from diet and 200 IU/d as supplemental cholecalciferol) and related nutrients (1.6 ± 0.4 g Ca/d an2016-01-01T00:00:00Z2016 Aug2025-04-04T10:11:33.1Z2019-03-27T02:19:01ZS-EPMC49582902733513910.3945/jn.116.229971