{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lo NC"],"funding":["European Research Council","Stanford University Center for African Studies","Doris Duke Charitable Foundation","Infectious Diseases Society of America","Mount Sinai Hospital-University Health Network AMO Innovation Fund","American Society of Tropical Medicine and Hygiene"],"pagination":["e0004894"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4978437"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(8)"],"pubmed_abstract":["<h4>Background</h4>A key epidemiologic feature of schistosomiasis is its focal distribution, which has important implications for the spatial targeting of preventive chemotherapy programs. We evaluated the diagnostic accuracy of a urine pooling strategy using a point-of-care circulating cathodic antigen (POC-CCA) cassette test for detection of Schistosoma mansoni, and employed simulation modeling to test the classification accuracy and efficiency of this strategy in determining where preventive chemotherapy is needed in low-endemicity settings.<h4>Methodology</h4>We performed a cross-sectional study involving 114 children aged 6-15 years in six neighborhoods in Azaguié Ahoua, south Côte d'Ivoire to characterize the sensitivity and specificity of the POC-CCA cassette test with urine samples"],"journal":["PLoS neglected tropical diseases"],"pubmed_title":["Evaluation of a Urine Pooling Strategy for the Rapid and Cost-Efficient Prevalence Classification of Schistosomiasis."],"pmcid":["PMC4978437"],"funding_grant_id":["Graduate Student Fellowship","Medical Scholars program","Benjamin H. Kean Fellowship in Tropical Medicine"],"pubmed_authors":["Lo NC","Bogoch II","Keiser J","Andrews JR","Bendavid E","Coulibaly JT","Utzinger J","N'Goran EK"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of a Urine Pooling Strategy for the Rapid and Cost-Efficient Prevalence Classification of Schistosomiasis.","description":"<h4>Background</h4>A key epidemiologic feature of schistosomiasis is its focal distribution, which has important implications for the spatial targeting of preventive chemotherapy programs. We evaluated the diagnostic accuracy of a urine pooling strategy using a point-of-care circulating cathodic antigen (POC-CCA) cassette test for detection of Schistosoma mansoni, and employed simulation modeling to test the classification accuracy and efficiency of this strategy in determining where preventive chemotherapy is needed in low-endemicity settings.<h4>Methodology</h4>We performed a cross-sectional study involving 114 children aged 6-15 years in six neighborhoods in Azaguié Ahoua, south Côte d'Ivoire to characterize the sensitivity and specificity of the POC-CCA cassette test with urine samples","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Aug","modification":"2025-05-29T22:27:07.958Z","creation":"2025-05-29T22:27:07.958Z"},"accession":"S-EPMC4978437","cross_references":{"pubmed":["27504954"],"doi":["10.1371/journal.pntd.0004894"]}}