{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mels CM"],"funding":["Metabolic Syndrome Institute, France","Roche Products (Pty) Ltd, South Africa","National Research Foundation","South African Medical Research Council"],"pagination":["9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5005872"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["38(1)"],"pubmed_abstract":["Inadequate substrate availability and increased nitric oxide synthase inhibitor levels attenuate nitric oxide (NO) synthesis, whereas increased vascular oxidative stress may lead to inactivation of NO. We compared markers of NO synthesis capacity and oxidative stress in a bi-ethnic male population. Inter-relationships of ambulatory blood pressure and urinary albumin-to-creatinine ratio with NO synthesis capacity and oxidative stress markers were investigated. NO synthesis capacity markers (L-arginine, asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA)) and oxidative stress markers (serum peroxides, total glutathione, glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), and catalase) were measured. Black men displayed higher blood pres"],"journal":["Age (Dordrecht, Netherlands)"],"pubmed_title":["The relationship of nitric oxide synthesis capacity, oxidative stress, and albumin-to-creatinine ratio in black and white men: the SABPA study."],"pmcid":["PMC5005872"],"funding_grant_id":["80643"],"pubmed_authors":["Schutte AE","Mels CM","Schutte R","Boger RH","Ware LJ","Smith W","Atzler D","Huisman HW","Schwedhelm E"],"additional_accession":[]},"is_claimable":false,"name":"The relationship of nitric oxide synthesis capacity, oxidative stress, and albumin-to-creatinine ratio in black and white men: the SABPA study.","description":"Inadequate substrate availability and increased nitric oxide synthase inhibitor levels attenuate nitric oxide (NO) synthesis, whereas increased vascular oxidative stress may lead to inactivation of NO. We compared markers of NO synthesis capacity and oxidative stress in a bi-ethnic male population. Inter-relationships of ambulatory blood pressure and urinary albumin-to-creatinine ratio with NO synthesis capacity and oxidative stress markers were investigated. NO synthesis capacity markers (L-arginine, asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA)) and oxidative stress markers (serum peroxides, total glutathione, glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), and catalase) were measured. Black men displayed higher blood pres","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Feb","modification":"2025-04-06T19:40:39.577Z","creation":"2019-03-27T02:23:03Z"},"accession":"S-EPMC5005872","cross_references":{"pubmed":["26767376"],"doi":["10.1007/s11357-016-9873-6"]}}