{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(6)"],"submitter":["Sosa-Jurado F"],"pubmed_abstract":["<h4>Background</h4>The hepatitis B virus (HBV) causes chronic hepatitis, hepatic cirrhosis, and hepatocellular carcinoma. Surface antigen (HBsAg) detection is a definitive test that can confirm HBV infection, while the presence of antibodies against the core protein (anti-HBc) suggests either a previous or ongoing infection or occult hepatitis B infection (OBI).<h4>Objectives</h4>The aim of the present study was to determine the prevalence of anti-HBc and HBsAg in blood donors. Further, the study aimed to estimate the anti-HBc level at which HBV DNA is detected in putative OBI cases, as well as to search for mutations in the \"a\" determinant associated with the non-detection of HBsAg in serum.<h4>Patients and methods</h4>We conducted a cross-sectional study from 2003-2009. The study include"],"journal":["Hepatitis monthly"],"pagination":["e36942"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5011399"],"repository":["biostudies-literature"],"pubmed_title":["Prevalence of Serologic Hepatitis B Markers in Blood Donors From Puebla, Mexico: The Association of Relatively High Levels of Anti-Core Antibodies With the Detection of Surface Antigen and Genomic DNA."],"pmcid":["PMC5011399"],"pubmed_authors":["Melendez-Mena D","Perez Zempoaltecalt C","Guzman-Flores B","Teresa Lopez Delgado M","Marquez-Dominguez L","Hilda Rosas-Murrieta N","Ramirez Rosete L","Patricia Sanchez Torres A","Sosa-Jurado F","Vallejo-Ruiz V","Santos-Lopez G","Bernal-Soto M","Reyes-Leyva J","Angel Mendoza Torres M"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence of Serologic Hepatitis B Markers in Blood Donors From Puebla, Mexico: The Association of Relatively High Levels of Anti-Core Antibodies With the Detection of Surface Antigen and Genomic DNA.","description":"<h4>Background</h4>The hepatitis B virus (HBV) causes chronic hepatitis, hepatic cirrhosis, and hepatocellular carcinoma. Surface antigen (HBsAg) detection is a definitive test that can confirm HBV infection, while the presence of antibodies against the core protein (anti-HBc) suggests either a previous or ongoing infection or occult hepatitis B infection (OBI).<h4>Objectives</h4>The aim of the present study was to determine the prevalence of anti-HBc and HBsAg in blood donors. Further, the study aimed to estimate the anti-HBc level at which HBV DNA is detected in putative OBI cases, as well as to search for mutations in the \"a\" determinant associated with the non-detection of HBsAg in serum.<h4>Patients and methods</h4>We conducted a cross-sectional study from 2003-2009. The study include","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Jun","modification":"2025-05-31T23:52:22.615Z","creation":"2025-05-31T23:52:22.615Z"},"accession":"S-EPMC5011399","cross_references":{"pubmed":["27630726"],"doi":["10.5812/hepatmon.36942"]}}