biostudies-literatureUnknown6Xin XCD147/EMMPRIN (extracellular matrix metalloproteinase inducer) plays an important role in tumor progression and a number of studies have suggested that it is an indicator of tumor prognosis. This current meta-analysis systematically reevaluated the predictive potential of CD147/EMMPRIN in various cancers. We searched PubMed and Embase databases to screen the literature. Fixed-effect and random-effect meta-analytical techniques were used to correlate CD147 expression with outcome measures. A total of 53 studies that included 68 datasets were eligible for inclusion in the final analysis. We found a significant association between CD147/EMMPRIN overexpression and adverse tumor outcomes, such as overall survival, disease-specific survival, progression-free survival, metastasis-free survival orScientific reports32804https://www.ebi.ac.uk/biostudies/studies/S-EPMC5016850biostudies-literatureCD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis.PMC5016850Gu HTan HShi RHua TZeng XWang HXin XJin ZLi MfalseCD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis.CD147/EMMPRIN (extracellular matrix metalloproteinase inducer) plays an important role in tumor progression and a number of studies have suggested that it is an indicator of tumor prognosis. This current meta-analysis systematically reevaluated the predictive potential of CD147/EMMPRIN in various cancers. We searched PubMed and Embase databases to screen the literature. Fixed-effect and random-effect meta-analytical techniques were used to correlate CD147 expression with outcome measures. A total of 53 studies that included 68 datasets were eligible for inclusion in the final analysis. We found a significant association between CD147/EMMPRIN overexpression and adverse tumor outcomes, such as overall survival, disease-specific survival, progression-free survival, metastasis-free survival or2016-01-01T00:00:00Z2016 Sep2025-04-21T16:37:33.588Z2019-03-27T02:23:51ZS-EPMC50168502760894010.1038/srep32804