{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ward JM"],"funding":["Lupus Foundation of America (CFW)","NIAID NIH HHS","National Institutes of Health","NIAMS NIH HHS","NIGMS NIH HHS"],"pagination":["213-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5021782"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9"],"pubmed_abstract":["Previously published studies revealed that variation in expression of the DNA-binding protein ARID3a in B lymphocytes from patients with systemic lupus erythematosus (SLE) correlated with levels of disease activity (\"Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A\" (J.M. Ward, K. Rose, C. Montgomery, I. Adrianto, J.A. James, J.T. Merrill et al., 2014) [1]). The data presented here compare DNA methylation patterns from SLE peripheral blood mononuclear cells obtained from samples with high numbers of ARID3a expressing B cells (ARID3a(H)) versus SLE samples with normal numbers of ARID3a(+) B cells (ARID3a(N)). The methylation data is available at the gene expression omnibus (GEO) repository, \"Gene Expression"],"journal":["Data in brief"],"pubmed_title":["Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels."],"pmcid":["PMC5021782"],"funding_grant_id":["P30 GM110766","U54 GM104938","GM104938","AR053483","R21 AI090343","R01 AR056360","U19 AI082714","P30 GM103510","GM103510","R01 AR063124","T32 AI007633","R01 AI044215","AIO90343","AI082714","R56 AI118836","AR063124","GM110766","AR056360","P30 AR053483","R01 AI118836","AI101934","U01 AI101934","AI044215"],"pubmed_authors":["Dozmorov MG","James JA","Wiley G","Ratliff ML","Guthridge JM","Webb CF","Gaffney PM","Ward JM"],"additional_accession":[]},"is_claimable":false,"name":"Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels.","description":"Previously published studies revealed that variation in expression of the DNA-binding protein ARID3a in B lymphocytes from patients with systemic lupus erythematosus (SLE) correlated with levels of disease activity (\"Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A\" (J.M. Ward, K. Rose, C. Montgomery, I. Adrianto, J.A. James, J.T. Merrill et al., 2014) [1]). The data presented here compare DNA methylation patterns from SLE peripheral blood mononuclear cells obtained from samples with high numbers of ARID3a expressing B cells (ARID3a(H)) versus SLE samples with normal numbers of ARID3a(+) B cells (ARID3a(N)). The methylation data is available at the gene expression omnibus (GEO) repository, \"Gene Expression","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Dec","modification":"2026-05-04T16:19:38.914Z","creation":"2019-03-27T02:24:09Z"},"accession":"S-EPMC5021782","cross_references":{"pubmed":["27656675"],"doi":["10.1016/j.dib.2016.08.049"]}}