biostudies-literatureWard JMLupus Foundation of America (CFW)NIAID NIH HHSNational Institutes of HealthNIAMS NIH HHSNIGMS NIH HHS213-9https://www.ebi.ac.uk/biostudies/studies/S-EPMC5021782biostudies-literatureUnknown9Previously published studies revealed that variation in expression of the DNA-binding protein ARID3a in B lymphocytes from patients with systemic lupus erythematosus (SLE) correlated with levels of disease activity ("Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A" (J.M. Ward, K. Rose, C. Montgomery, I. Adrianto, J.A. James, J.T. Merrill et al., 2014) [1]). The data presented here compare DNA methylation patterns from SLE peripheral blood mononuclear cells obtained from samples with high numbers of ARID3a expressing B cells (ARID3a(H)) versus SLE samples with normal numbers of ARID3a(+) B cells (ARID3a(N)). The methylation data is available at the gene expression omnibus (GEO) repository, "Gene ExpressionData in briefExpression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels.PMC5021782P30 GM110766U54 GM104938GM104938AR053483R21 AI090343R01 AR056360U19 AI082714P30 GM103510GM103510R01 AR063124T32 AI007633R01 AI044215AIO90343AI082714R56 AI118836AR063124GM110766AR056360P30 AR053483R01 AI118836AI101934U01 AI101934AI044215Dozmorov MGJames JAWiley GRatliff MLGuthridge JMWebb CFGaffney PMWard JMfalseExpression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels.Previously published studies revealed that variation in expression of the DNA-binding protein ARID3a in B lymphocytes from patients with systemic lupus erythematosus (SLE) correlated with levels of disease activity ("Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A" (J.M. Ward, K. Rose, C. Montgomery, I. Adrianto, J.A. James, J.T. Merrill et al., 2014) [1]). The data presented here compare DNA methylation patterns from SLE peripheral blood mononuclear cells obtained from samples with high numbers of ARID3a expressing B cells (ARID3a(H)) versus SLE samples with normal numbers of ARID3a(+) B cells (ARID3a(N)). The methylation data is available at the gene expression omnibus (GEO) repository, "Gene Expression2016-01-01T00:00:00Z2016 Dec2026-05-04T16:19:38.914Z2019-03-27T02:24:09ZS-EPMC50217822765667510.1016/j.dib.2016.08.049